Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24627426 | 1.00 | KMT2A (0.55) | KMT2AMAOBNR4A2RAB9AMEN1 | |
| SCHEMBL24627541 | 0.87 | EGFR (0.49) | KMT2AMAOBNR4A2RAB9AMEN1 | |
| SCHEMBL29777992 | 0.81 | L3MBTL1 (0.60) | KMT2AMAOBNR4A2RAB9ASMPD1 | |
| SCHEMBL29777971 | 0.78 | ALDH1A1 (0.43) | — | |
| SCHEMBL7367495 | 0.75 | ALDH1A1 (0.58) | KMT2A | |
| SCHEMBL9536302 | 0.75 | LTA4H (0.47) | LTB4RLTB4R2 | |
| SCHEMBL5968220 | 0.74 | RAB9A (0.64) | KMT2ARAB9AMEN1ESR1F10 | |
| SCHEMBL10466517 | 0.74 | MAOB (0.69) | KMT2AMAOBNR4A2MEN1SMPD1 | |
| SCHEMBL24627626 | 0.73 | KMT2A (0.51) | KMT2AESR1SMPD1F10 | |
| SCHEMBL12134478 | 0.73 | ESR1 (0.69) | KMT2ARAB9AMEN1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148879-A1 | QUINAZOLINE DERIVATIVES USEFUL AS MODULATORS OF ACKR3 | STICHTING VU (NL) | 2022-07-14 | — | — | WO | disclosed |