Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3101115 | 0.90 | MAPT (0.40) | PDK2OPRD1LMNAMAPTKDM4E | |
| SCHEMBL3970823 | 0.87 | MAPT (0.36) | PDK2LMNAMAPTHSD11B1KDM4E | |
| SCHEMBL3977568 | 0.86 | HSD11B1 (0.33) | MAPTHSD11B1 | |
| SCHEMBL3972514 | 0.82 | MGLL (0.33) | HSD11B1 | |
| SCHEMBL3970810 | 0.79 | AKT1 (0.32) | AKT1HSD11B1 | |
| SCHEMBL3972108 | 0.78 | HSD11B1 (0.33) | HSD11B1KDM4E | |
| SCHEMBL3907137 | 0.78 | PDE2A (0.32) | — | |
| SCHEMBL3095009 | 0.78 | NAMPT (0.39) | HSD11B1 | |
| SCHEMBL2973860 | 0.77 | HSD11B1 (0.31) | HSD11B1 | |
| SCHEMBL3970072 | 0.77 | KDM4E (0.34) | HSD11B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7776874-B2 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION (US) | 2010-08-17 | — | — | US | disclosed |