Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 10/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 3/20 | 0.36 |
| ▸ | CPA1 | P15085 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29798282 | 0.73 | MAPT (0.42) | MAPTCPB2GABRPGABRDGABRA1 | |
| SCHEMBL23327043 | 0.73 | MAPT (0.42) | MAPTCPB2GABRPGABRDGABRA1 | |
| SCHEMBL4154226 | 0.71 | NFKB1 (0.54) | MAPTCPB2GABRPGABRDGABRA1 | |
| SCHEMBL10723761 | 0.70 | RAB9A (0.54) | MAPTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL18924321 | 0.69 | CPB2 (0.50) | CPB2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10130836 | 0.69 | CPB2 (0.57) | CPB2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2823763 | 0.68 | RAB9A (0.57) | MAPTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13357005 | 0.68 | CPB2 (0.53) | CPB2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL294092 | 0.67 | GABRP (0.50) | MAPTCPB2GABRPGABRDGABRA1 | |
| SCHEMBL5079022 | 0.67 | CPB2 (0.65) | MAPTCPB2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11427542-B2 | Compounds for treatment of cardiac arrhythmias and heart failure | ELEX BIOTECH, INC. (US) | 2022-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11427542-B2 | Compounds for treatment of cardiac arrhythmias and heart failure | RYR2, RYR1, CACNA1F | MAPT 341/4885CPB2 2953/4885GABRP 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.