Sugi Predict

Sugi Predict / Compounds / SCHEMBL2979889

SCHEMBL2979889

SCHEMBL2979889

C[Si](Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA4 P22748 1/20 0.48
▸ LTA4H P09960 4/20 0.45
▸ TSHR P16473 1/20 0.45
▸ CA1 P00915 1/20 0.39
▸ CA2 P00918 1/20 0.39
▸ CA9 Q16790 1/20 0.39
▸ KCNA3 P22001 1/20 0.38
▸ CA5A P35218 1/20 0.36
▸ CA5B Q9Y2D0 1/20 0.36
▸ NR1H2 P55055 1/20 0.35
▸ BAX Q07812 1/20 0.35
▸ MAOA P21397 1/20 0.35
▸ LMNA P02545 2/20 0.34
▸ HTR1B P28222 2/20 0.34
▸ HTR1D P28221 1/20 0.34
▸ PGR P06401 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ TAAR1 Q96RJ0 1/20 0.33
▸ SOS1 Q07889 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL276553 0.82 CA4 (0.48) CA4LTA4HTSHRCA1CA2
SCHEMBL275158 0.75 LTA4H (0.50) CA4LTA4HTSHRCA1CA2
SCHEMBL22478812 0.71 LTA4H (0.45) CA4LTA4HTSHRCA1CA2
SCHEMBL896124 0.71 LTA4H (0.45) CA4LTA4HTSHRCA1CA2
SCHEMBL705307 0.71 LTA4H (0.45) CA4LTA4HTSHRCA1CA2
SCHEMBL702313 0.71 LTA4H (0.45) CA4LTA4HTSHRCA1CA2
SCHEMBL17385965 0.71 LTA4H (0.45) CA4LTA4HTSHRCA1CA2
SCHEMBL23365066 0.70 CA4 (0.42) CA4LTA4HTSHRKCNA3LMNA
SCHEMBL2981674 0.70 CA4 (0.42) CA4LTA4HTSHRKCNA3LMNA
SCHEMBL21694127 0.69 LTA4H (0.43) CA4LTA4HTSHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070282121-A1 INTERMEDIATES FOR THE SYNTHESIS OF POLYPROPIONATE ANTIBIOTICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-12-06 — — US claimed
US-7297807-B1 Intermediates for the synthesis of polypropionate antibiotics THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2007-11-20 — — US claimed
EP-3502181-B1 CROSSLINKED RUBBER ZEON CORP (JP) 2023-09-27 — — EP disclosed
CN-116769296-A Curable composition 株式会社钟化 2023-09-19 — — CN disclosed
WO-2023167011-A1 CURABLE COMPOSITION 株式会社カネカ 2023-09-07 — — WO disclosed
CN-113795547-B Curable composition and cured product 株式会社钟化 2023-06-23 — — CN disclosed
US-20220403056-A1 CURED RUBBER NETWORK WITH COVALENT AND HYDROGEN-BONDED CROSSLINKS BRIDGESTONE CORPORATION (JP) 2022-12-22 — — US disclosed
US-20220380522-A1 RING-OPENED COPOLYMER ZEON CORPORATION (JP) 2022-12-01 — — US disclosed
EP-4058487-A2 CURED RUBBER NETWORK WITH COVALENT AND HYDROGEN-BONDED CROSSLINKS BRIDGESTONE CORPORATION (JP) 2022-09-21 — — EP disclosed
EP-3950832-A1 CURABLE COMPOSITION AND CURED PRODUCT Kaneka Corporation (JP) 2022-02-09 — — EP disclosed
US-20220002541-A1 CURABLE COMPOSITION AND CURED PRODUCT KANEKA CORPORATION (JP) 2022-01-06 — — US disclosed
US-20130071732-A1 NONAQUEOUS ELECTROLYTE SOLUTION CONTAINING SILYL ESTER GROUP-CONTAINING PHOSPHONIC ACID DERIVATIVE, AND LITHIUM SECONDARY BATTERY MITSUI CHEMICALS, INC. (JP) 2013-03-21 — — US disclosed
EP-2524936-A1 RING-OPENING POLYMER OF CYCLOPENTENE AND METHOD FOR PRODUCING SAME Zeon Corporation (JP) 2012-11-21 — — EP disclosed
US-20120204940-A1 POLYVINYL ACETAL LAMINATE AND USE THEREOF KURARAY CO., LTD. (JP) 2012-08-16 — — US disclosed
EP-2463095-A1 POLYVINYL ACETAL LAMINATE AND USE THEREOF Kuraray Co., Ltd. (JP) 2012-06-13 — — EP disclosed
US-20100179312-A1 CONVERTIBLE NUCLEOSIDE DERIVATIVES LAKSHMAN MAHESH K 2010-07-15 — — US disclosed
WO-2008045535-A2 CONVERTIBLE NUCLEOSIDE DERIVATIVES RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2008-04-17 — — WO disclosed
US-7339066-B1 Intermediates for the synthesis of polypropionate antibiotics THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2008-03-04 — — US disclosed
US-20070282121-A1 INTERMEDIATES FOR THE SYNTHESIS OF POLYPROPIONATE ANTIBIOTICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-12-06 — — US disclosed
US-7297807-B1 Intermediates for the synthesis of polypropionate antibiotics THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2007-11-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070282121-A1 INTERMEDIATES FOR THE SYNTHESIS OF POLYPROPIONATE ANTIBIOTICS DHPS, EMG1, RPN1 CA4 4411/4885LTA4H 2060/4885TSHR 2496/4885
US-20100179312-A1 CONVERTIBLE NUCLEOSIDE DERIVATIVES PNP, NUDT1, NUDT14 CA4 4219/4885LTA4H 2367/4885TSHR 3560/4885
US-20130071732-A1 NONAQUEOUS ELECTROLYTE SOLUTION CONTAINING SILYL ESTER GROUP-CONTAINING PHOSPHONIC ACID DERIVATIVE, AND LITHIUM SECONDARY BATTERY PHOSPHO1, PSPH, SGK2 CA4 345/4885LTA4H 1540/4885TSHR 4500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.