Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.38 |
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 4/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29814609 | 0.87 | REN (0.41) | FAPREN | |
| SCHEMBL29800885 | 0.83 | NAA50 (0.47) | CTSLCTSSCTSKNAA50CTSH | |
| SCHEMBL31067246 | 0.77 | PTPN1 (0.43) | NAA50APLNR | |
| SCHEMBL5367479 | 0.76 | F2 (0.42) | REN | |
| SCHEMBL29904041 | 0.75 | APLNR (0.41) | FAPNAA50APLNR | |
| SCHEMBL29800494 | 0.75 | OPRM1 (0.44) | APLNR | |
| SCHEMBL30493464 | 0.74 | APLNR (0.42) | FAPNAA50APLNR | |
| SCHEMBL29801041 | 0.74 | OPRM1 (0.55) | — | |
| SCHEMBL5495351 | 0.74 | NAA50 (0.54) | NAA50APLNR | |
| SCHEMBL31297104 | 0.73 | REN (0.46) | FAPAPLNRREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422799-B | Docetaxel liver cancer-resisting targeted prodrug and medicinal application thereof | 复旦大学 | 2022-07-29 | — | — | CN | disclosed |