Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.37 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.37 |
| ▸ | GRPR | P30550 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067246 | 0.93 | PTPN1 (0.43) | NAA50APLNROPRD1PTPN1NTSR1 | |
| SCHEMBL29904041 | 0.92 | APLNR (0.41) | NAA50APLNROPRM1OPRD1PTPN1 | |
| SCHEMBL29800494 | 0.91 | OPRM1 (0.44) | APLNROPRM1OPRD1NMUR2NMUR1 | |
| SCHEMBL30493464 | 0.90 | APLNR (0.42) | NAA50APLNROPRM1OPRD1PTPN1 | |
| SCHEMBL5495351 | 0.90 | NAA50 (0.54) | NAA50APLNRNTSR1NMUR2NMUR1 | |
| SCHEMBL30563219 | 0.89 | NAA50 (0.44) | NAA50PTPN1NTSR1 | |
| SCHEMBL29904042 | 0.87 | APLNR (0.42) | APLNROPRM1OPRD1PTPN1NTSR1 | |
| SCHEMBL29569246 | 0.87 | NTSR1 (0.44) | APLNROPRD1PTPN1NTSR1 | |
| SCHEMBL29800900 | 0.86 | NTSR1 (0.48) | OPRD1PTPN1NTSR1 | |
| SCHEMBL30933089 | 0.85 | NAA50 (0.48) | NAA50APLNRNTSR1NMUR2NMUR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422799-B | Docetaxel liver cancer-resisting targeted prodrug and medicinal application thereof | 复旦大学 | 2022-07-29 | — | — | CN | claimed |
| CN-109422799-B | Docetaxel liver cancer-resisting targeted prodrug and medicinal application thereof | 复旦大学 | 2022-07-29 | — | — | CN | disclosed |