Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | APEX1 | P27695 | 2/20 | 0.32 |
| ▸ | LDHA | P00338 | 2/20 | 0.32 |
| ▸ | LDHB | P07195 | 2/20 | 0.32 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.32 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1007227 | 0.89 | NOTUM (0.35) | NOTUMMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL3074823 | 0.88 | NOTUM (0.33) | NOTUMMAPTKDM4EMEN1KMT2A | |
| SCHEMBL1376717 | 0.82 | HMGB1 (0.33) | NOTUMMAPTKDM4EMEN1KMT2A | |
| SCHEMBL1007226 | 0.82 | LDHA (0.33) | NOTUMMAPTKDM4EMEN1KMT2A | |
| SCHEMBL1646383 | 0.82 | ALDH1A1 (0.31) | NOTUMALDH1A1LDHALDHB | |
| SCHEMBL3068519 | 0.82 | ALDH1A1 (0.31) | NOTUMALDH1A1LDHALDHB | |
| SCHEMBL3069564 | 0.80 | ALDH1A1 (0.30) | ALDH1A1LDHALDHB | |
| SCHEMBL7727731 | 0.80 | KDM4E (0.32) | KDM4EL3MBTL1 | |
| SCHEMBL27915392 | 0.79 | PKM (0.31) | NOTUMALDH1A1LDHALDHB | |
| SCHEMBL1643688 | 0.79 | ALDH1A1 (0.31) | NOTUMALDH1A1LDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1842870-B1 | Polymide silicone resin and thermosetting composition comprising the same | SHINETSU CHEMICAL CO (JP) | 2014-05-21 | — | — | EP | disclosed |
| US-7781541-B2 | Polyimide silicone resin and thermosetting composition comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-08-24 | — | — | US | disclosed |
| EP-1842870-A2 | Polymide silicone resin and thermosetting composition comprising the same | Shin-Etsu Chemical Company, Ltd. (JP) | 2007-10-10 | — | — | EP | disclosed |
| US-20070197680-A1 | Polyimide silicone resin and thermosetting composition comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-08-23 | — | — | US | disclosed |