SCHEMBL1007226

SCHEMBL1007226

Cc1c(CC2CO2)c(CC2CO2)cc(C(=O)O)c1C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LDHA P00338 3/20 0.33
LDHB P07195 3/20 0.33
NOTUM Q6P988 1/20 0.33
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPT P10636 1/20 0.32
MEN1 O00255 1/20 0.31
APEX1 P27695 1/20 0.31
KMT2A Q03164 1/20 0.31
HMGB1 P09429 1/20 0.30
CXCL12 P48061 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3074823 0.89 NOTUM (0.33) LDHALDHBNOTUMKDM4EL3MBTL1
SCHEMBL7727731 0.87 KDM4E (0.32) KDM4EL3MBTL1
SCHEMBL1376717 0.86 HMGB1 (0.33) LDHALDHBNOTUMKDM4EL3MBTL1
SCHEMBL1644098 0.83
SCHEMBL2980272 0.82 NOTUM (0.34) LDHALDHBNOTUMKDM4EL3MBTL1
SCHEMBL3076528 0.81 HMGB1 (0.33) LDHALDHBMEN1KMT2AHMGB1
SCHEMBL3069660 0.81 HMGB1 (0.36) LDHALDHBHMGB1CXCL12
SCHEMBL6689310 0.81 HMGB1 (0.31) HMGB1CXCL12
SCHEMBL1007227 0.81 NOTUM (0.35) LDHALDHBNOTUMKDM4EL3MBTL1
SCHEMBL3076497 0.80 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2256163-B1 EPOXY RESIN COMPOSITION, FIBER-REINFORCED COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME TORAY INDUSTRIES (JP) 2018-11-14 EP disclosed
US-20160159993-A1 EPOXY RESIN COMPOSITION, FIBER-REINFORCED COMPOSITE MATERIAL, AND METHOD FOR PRODUCING THE SAME TORAY INDUSTRIES, INC. (JP) 2016-06-09 US disclosed
EP-2284165-B1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION SAN APRO LTD (JP) 2013-02-20 EP disclosed
US-8278030-B2 Sulfonium salt, photoacid generator, and photocurable composition and cured body thereof SAN-APRO LIMITED (JP) 2012-10-02 US disclosed
EP-2488585-A1 METHOD FOR CONTINUOUSLY PRODUCING POLYESTER MIXTURES BASF SE (DE) 2012-08-22 EP disclosed
US-20110097568-A1 EPOXY RESIN COMPOSITION, FIBER-REINFORCED COMPOSITE MATERIAL, AND METHOD FOR PRODUCING THE SAME TORAY INDUSTRIES, INC 2011-04-28 US disclosed
WO-2011045293-A1 METHOD FOR CONTINUOUSLY PRODUCING POLYESTER MIXTURES BASF SE (DE) 2011-04-21 WO disclosed
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF SAN-APRO LIMITED (JP) 2011-02-17 US disclosed
EP-2284165-A1 PHOSPHONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION San-Apro Limited (JP) 2011-02-16 EP disclosed
EP-2268702-A1 METHOD FOR THE CONTINUOUS PRODUCTION OF BIODEGRADABLE POLYESTERS BASF SE (DE) 2011-01-05 EP disclosed
EP-2268704-A1 METHOD FOR THE CONTINUOUS PRODUCTION OF BIODEGRADABLE POLYESTERS BASF SE (DE) 2011-01-05 EP disclosed
EP-2256163-A1 EPOXY RESIN COMPOSITION, FIBER-REINFORCED COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME Toray Industries, Inc. (JP) 2010-12-01 EP disclosed
WO-2009127555-A1 METHOD FOR THE CONTINUOUS PRODUCTION OF BIODEGRADABLE POLYESTERS BASF SE (DE) 2009-10-22 WO disclosed
WO-2009127556-A1 METHOD FOR THE CONTINUOUS PRODUCTION OF BIODEGRADABLE POLYESTERS BASF SE (DE) 2009-10-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF ARSA, ASIC1, TST LDHA 4180/4885LDHB 4042/4885NOTUM 1588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.