Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 5/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 2/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22931772 | 1.00 | LIPE (0.37) | LIPEABCG2MT-CO2DYRK3CCNA2 | |
| SCHEMBL29420832 | 0.90 | RXRA (0.32) | LIPEMT-CO2RXRANR1H2NR1H3 | |
| SCHEMBL22931775 | 0.90 | RXRA (0.32) | LIPEMT-CO2RXRANR1H2NR1H3 | |
| SCHEMBL22932341 | 0.80 | XDH (0.33) | LIPEMT-CO2MEN1KMT2ARXRA | |
| SCHEMBL22932332 | 0.80 | BCHE (0.34) | MAPTLMNACACNA1BCACNA1C | |
| SCHEMBL24755009 | 0.80 | LIPE (0.35) | LIPEABCG2MT-CO2DYRK3CCNA2 | |
| SCHEMBL29806705 | 0.80 | LIPE (0.35) | LIPEABCG2MT-CO2DYRK3CCNA2 | |
| SCHEMBL22931809 | 0.78 | KDM4E (0.40) | LIPEMT-CO2MEN1KMT2ARXRA | |
| SCHEMBL22931787 | 0.78 | MT-CO2 (0.37) | LIPEMT-CO2RXRANR1H2NR1H3 | |
| SCHEMBL22931784 | 0.77 | TRPM8 (0.33) | RXRANR1H2NR1H3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003983-A1 | 1,2,4-OXADIAZOL-5-ONE DERIVATIVES FOR THE TREATMENT OF CANCER | Basilea Pharmaceutica International AG (CH) | 2022-06-01 | — | — | EP | disclosed |