⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2975120 | 0.90 | — | — | |
| SCHEMBL2980822 | 0.88 | GRIN2B (0.44) | — | |
| SCHEMBL2982101 | 0.82 | DCUN1D1 (0.42) | — | |
| SCHEMBL2975028 | 0.81 | ARG1 (0.44) | — | |
| SCHEMBL3598760 | 0.79 | TP53 (0.44) | — | |
| SCHEMBL3598762 | 0.79 | CCR5 (0.46) | — | |
| SCHEMBL2980730 | 0.78 | PRCP (0.36) | — | |
| SCHEMBL2979865 | 0.77 | HTR1A (0.45) | — | |
| SCHEMBL2970167 | 0.77 | SIGMAR1 (0.49) | — | |
| Hydrochloric Acid SCHEMBL2971261 | 0.76 | SIGMAR1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781590-B2 | Piperidinylalkylcarbamate derivatives, methods for their preparation and the therapeutic use thereof as fatty acid amido hydrolase enzyme inhibitors | SANOFI-AVENTIS (FR) | 2010-08-24 | — | — | US | disclosed |
| US-20070021403-A1 | PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2007-01-25 | — | — | US | disclosed |