Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | IRS1 | P35568 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31494436 | 0.80 | RAB9A (0.46) | NOTUMSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL29808208 | 0.77 | HPGD (0.54) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL29808087 | 0.77 | KDM4E (0.49) | SMN1; SMN2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL29807808 | 0.77 | TSHR (0.61) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL11351553 | 0.76 | L3MBTL1 (0.64) | NOTUMSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL5695138 | 0.74 | HSD17B10 (0.65) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL11357489 | 0.71 | HDAC8 (0.56) | NOTUMSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL11161665 | 0.71 | NOTUM (0.54) | NOTUMSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL11152712 | 0.70 | NOTUM (0.49) | NOTUMSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL29808335 | 0.69 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220274968-A1 | Oxazole And Oxadiazole Derivatives Useful As Agonists Of Free Fatty Acid Receptor 1 | GBIOTECH S.À.R.L. (CH) | 2022-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220274968-A1 | Oxazole And Oxadiazole Derivatives Useful As Agonists Of Free Fatty Acid Receptor 1 | FFAR2, FFAR1, FFAR3 | NOTUM 1056/4885SMN1; SMN2 3576/4885ALDH1A1 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.