SCHEMBL29808674

SCHEMBL29808674

Brc1ccc(-c2c3nc(c(-c4ccc(Br)s4)c4ccc([nH]4)c(-c4ccc(Br)s4)c4nc(c(-c5ccc(Br)s5)c5ccc2[nH]5)C=C4)C=C3)s1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 3/20 0.41
▸ TOP1 P11387 2/20 0.41
▸ CYCS P99999 2/20 0.40
▸ ENPP2 Q13822 1/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ ALOX12 P18054 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12884578 0.72 TERT (0.49) TERTTOP1CYCSENPP2HSD17B10
SCHEMBL4881460 0.70 TERT (0.46) TERTTOP1CYCSMEN1MAPT
SCHEMBL30039384 0.70 TERT (0.46) TERTTOP1CYCSMEN1MAPT
SCHEMBL3041824 0.69 TOP1 (0.60) TERTTOP1CYCSENPP2
SCHEMBL31258522 0.69 TERT (0.45) TERTTOP1CYCSMEN1MAPT
SCHEMBL1409958 0.69 TOP1 (0.45) TERTTOP1CYCSENPP2
SCHEMBL17442979 0.68 TERT (0.51) TERTTOP1CYCSENPP2
SCHEMBL29737292 0.68 TOP1 (0.58) TERTTOP1CYCSENPP2
SCHEMBL29002878 0.68 TOP1 (0.58) TERTTOP1CYCSENPP2
SCHEMBL28672107 0.68 TOP1 (0.58) TERTTOP1CYCSENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220395819-A1 PORPHYRIN-BASED CATALYSTS FOR WATER SPLITTING UNIV KING FAISAL (SA) 2022-12-15 — — US disclosed
US-11446648-B2 Porphyrin-based catalysts for water splitting King Faisal University (SA) 2022-09-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11446648-B2 Porphyrin-based catalysts for water splitting PPOX, FTH1, TPR TERT 241/4885TOP1 2352/4885CYCS 232/4885
US-20220395819-A1 PORPHYRIN-BASED CATALYSTS FOR WATER SPLITTING PPOX, FTH1, TPR TERT 241/4885TOP1 2352/4885CYCS 232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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