Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 0.72 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.56 |
| ▸ | S100A4 | P26447 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941746 | 1.00 | SRD5A2 (0.72) | SRD5A2SRD5A1RAB9ANPC1MAPT | |
| SCHEMBL15897526 | 0.93 | SRD5A2 (0.63) | SRD5A2SRD5A1RAB9ANPC1MAPT | |
| SCHEMBL15106295 | 0.91 | RAB9A (0.77) | SRD5A2SRD5A1RAB9ANPC1MAPT | |
| SCHEMBL407340 | 0.86 | MAPT (0.82) | SRD5A2SRD5A1RAB9ANPC1MAPT | |
| SCHEMBL11818520 | 0.85 | SRD5A2 (0.77) | SRD5A2SRD5A1RAB9ANPC1MAPT | |
| SCHEMBL10081754 | 0.84 | SRD5A2 (1.00) | SRD5A2SRD5A1RAB9ANPC1MITF | |
| SCHEMBL5687425 | 0.81 | SRD5A2 (0.66) | SRD5A2SRD5A1RAB9ANPC1MAPT | |
| SCHEMBL8253223 | 0.80 | NPC1 (0.61) | SRD5A2SRD5A1RAB9ANPC1MAPT | |
| SCHEMBL30692090 | 0.79 | RAB9A (1.00) | SRD5A2RAB9ANPC1MAPTHSD17B1 | |
| SCHEMBL3399487 | 0.79 | RAB9A (1.00) | SRD5A2RAB9ANPC1MAPTHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310373-A1 | METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2023-10-05 | — | — | US | disclosed |
| CN-108707140-B | Protease C inhibitors | 勃林格殷格翰国际有限公司 | 2022-07-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230310373-A1 | METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | CTSC, CTSG, CTSZ | SRD5A2 2195/4885SRD5A1 1927/4885RAB9A 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.