Sugi Predict

Sugi Predict / Compounds / SCHEMBL29811048

SCHEMBL29811048

SCHEMBL29811048

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KEAP1 Q14145 1/20 0.62
▸ GLP1R P43220 13/20 0.58
▸ CALCR P30988 4/20 0.57
▸ PTH1R Q03431 1/20 0.55
▸ SCTR P47872 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29461471 0.95 KEAP1 (0.56) KEAP1GLP1RCALCR
SCHEMBL30168767 0.93 KEAP1 (0.59) KEAP1GLP1RSCTR
SCHEMBL29836276 0.92 KEAP1 (0.57) KEAP1GLP1RCALCRSCTR
SCHEMBL30168691 0.91 KEAP1 (0.56) KEAP1GLP1RSCTR
SCHEMBL30262254 0.90 KEAP1 (0.60) KEAP1GLP1RCALCRPTH1R
SCHEMBL31182880 0.90 CALCR (0.67) GLP1RCALCR
SCHEMBL30168694 0.90 KEAP1 (0.59) KEAP1GLP1R
SCHEMBL30168693 0.90 F2 (0.56) KEAP1GLP1RSCTR
SCHEMBL30168734 0.90 F2 (0.56) KEAP1GLP1RSCTR
SCHEMBL30168702 0.89 MAPK8 (0.56) KEAP1GLP1RCALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-08-10 — — US disclosed
US-20230066762-A1 IMMUNOGENIC COMPOSITION GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-03-02 — — US disclosed
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-09-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 KEAP1 3572/4885GLP1R 2107/4885CALCR 415/4885
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 KEAP1 3572/4885GLP1R 2107/4885CALCR 415/4885
US-20230066762-A1 IMMUNOGENIC COMPOSITION CXCL10, CCL2, CCL11 KEAP1 2393/4885GLP1R 2834/4885CALCR 1308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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