Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.41 |
| ▸ | IL1RN | P18510 | 3/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 3/20 | 0.40 |
| ▸ | GLP1R | P43220 | 1/20 | 0.39 |
| ▸ | SCTR | P47872 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100933 | 1.00 | OPRM1 (0.47) | OPRM1OPRD1NPY1RNPY2RNPY4R | |
| SCHEMBL29815391 | 0.86 | NPY4R (0.51) | OPRM1OPRD1NPY1RNPY2RNPY4R | |
| SCHEMBL5699005 | 0.85 | BACE1 (0.49) | NPY1RNPY2RNPY4RBACE1BACE2 | |
| SCHEMBL5699001 | 0.85 | BACE1 (0.49) | NPY1RNPY2RNPY4RBACE1BACE2 | |
| SCHEMBL29531471 | 0.85 | ACE (0.47) | OPRD1NPY1RNPY2RNPY4RFOLH1 | |
| SCHEMBL30505408 | 0.85 | BACE1 (0.54) | NPY1RNPY2RNPY4RBACE1BACE2 | |
| SCHEMBL29629478 | 0.84 | LNPEP (0.44) | OPRM1OPRD1NPY1RNPY2RNPY4R | |
| SCHEMBL4935995 | 0.84 | OPRM1 (0.42) | OPRM1OPRD1BACE1IL1RNERAP2 | |
| SCHEMBL5526723 | 0.84 | OPRM1 (0.42) | OPRM1OPRD1BACE1IL1RNERAP2 | |
| SCHEMBL30799304 | 0.84 | NPY4R (0.51) | OPRM1NPY1RNPY2RNPY4RIL1RN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210113-B1 | METHODS FOR THE DETECTION OF GLYCATED HEMOGLOBIN | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2015-05-27 | — | — | EP | claimed |
| US-8715942-B2 | Methods for the detection of glycated hemoglobin | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2014-05-06 | — | — | US | claimed |
| WO-2009067421-A9 | METHODS FOR THE DETECTION OF GLYCATED HEMOGLOBIN | SIEMENS HEATHCARE DIAGNOSTICS INC. (US) | 2010-11-11 | — | — | WO | claimed |
| US-20100273181-A1 | METHODS FOR THE DETECTION OF GLYCATED HEMOGLOBIN | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-10-28 | — | — | US | claimed |
| EP-2210113-A1 | METHODS FOR THE DETECTION OF GLYCATED HEMOGLOBIN | Siemens Healthcare Diagnostics Inc. (US) | 2010-07-28 | — | — | EP | claimed |
| WO-2009067421-A1 | METHODS FOR THE DETECTION OF GLYCATED HEMOGLOBIN | SIEMENS HEATHCARE DIAGNOSTICS INC. (US) | 2009-05-28 | — | — | WO | claimed |
| EP-2210113-B1 | METHODS FOR THE DETECTION OF GLYCATED HEMOGLOBIN | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2015-05-27 | — | — | EP | disclosed |
| US-8715942-B2 | Methods for the detection of glycated hemoglobin | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2014-05-06 | — | — | US | disclosed |
| WO-2009067421-A9 | METHODS FOR THE DETECTION OF GLYCATED HEMOGLOBIN | SIEMENS HEATHCARE DIAGNOSTICS INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| US-20100273181-A1 | METHODS FOR THE DETECTION OF GLYCATED HEMOGLOBIN | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-10-28 | — | — | US | disclosed |
| EP-2210113-A1 | METHODS FOR THE DETECTION OF GLYCATED HEMOGLOBIN | Siemens Healthcare Diagnostics Inc. (US) | 2010-07-28 | — | — | EP | disclosed |
| WO-2009067421-A1 | METHODS FOR THE DETECTION OF GLYCATED HEMOGLOBIN | SIEMENS HEATHCARE DIAGNOSTICS INC. (US) | 2009-05-28 | — | — | WO | disclosed |