Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29829591 | 0.84 | CASR (0.60) | TLR8CASRSIGMAR1MEN1KMT2A | |
| SCHEMBL29829518 | 0.81 | CASR (0.60) | TLR8CASRSIGMAR1LMNAMAPT | |
| SCHEMBL29829544 | 0.81 | CASR (0.49) | TLR8NPY1RCASRPDE10ASIGMAR1 | |
| SCHEMBL29829974 | 0.80 | CASR (0.53) | TLR8L3MBTL1CASRSIGMAR1MAPT | |
| SCHEMBL29412097 | 0.74 | L3MBTL1 (0.50) | L3MBTL1SIGMAR1LMNAMEN1PKM | |
| SCHEMBL14685298 | 0.69 | PDE10A (0.53) | TLR8CASRPDE10AMEN1PKM | |
| SCHEMBL7962010 | 0.69 | NPY1R (0.77) | NPY1R | |
| SCHEMBL16512961 | 0.68 | TLR8 (1.00) | TLR8CASRMAPT | |
| SCHEMBL29829733 | 0.68 | TLR8 (0.48) | TLR8NPY1RCASRMEN1KMT2A | |
| SCHEMBL3882681 | 0.68 | RAB9A (0.62) | PDE10AMEN1PKMKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978301-B | Benzimidazole compound with endothelial lipase inhibition effect and application thereof | 盐城师范学院 | 2022-08-02 | — | — | CN | disclosed |