Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21593100 | 1.00 | ACHE (0.38) | ACHEALDH1A1LMNAHPGDHTT | |
| SCHEMBL21593181 | 0.94 | HTR6 (0.35) | ACHEALDH1A1LMNAHPGDHTT | |
| SCHEMBL23751199 | 0.93 | ALDH1A1 (0.38) | ALDH1A1LMNAHPGDHTTKMT2A | |
| SCHEMBL21593132 | 0.92 | ACHE (0.40) | ACHEALDH1A1LMNAHPGDHTT | |
| SCHEMBL21593076 | 0.92 | ACHE (0.39) | ACHEALDH1A1LMNAHPGDHTT | |
| SCHEMBL29836556 | 0.92 | ACHE (0.39) | ACHEALDH1A1LMNAHPGDHTT | |
| SCHEMBL21593186 | 0.91 | HTR6 (0.36) | ALDH1A1LMNAHPGDHTTHTR6 | |
| SCHEMBL21593133 | 0.91 | GCK (0.35) | ACHEALDH1A1LMNAHPGDHTT | |
| SCHEMBL21593131 | 0.91 | ACHE (0.38) | ACHEALDH1A1LMNAHPGDHTT | |
| SCHEMBL23762108 | 0.91 | ACHE (0.42) | ACHEALDH1A1LMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807273-B1 | AZAINDOLE DERIVATIVES AS RHO-KINASE INHIBITORS | CHIESI FARM SPA (IT) | 2022-08-03 | — | — | EP | disclosed |