SCHEMBL29844064

SCHEMBL29844064

Cc1cc(C)c(-n2cnc(C)c2C)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
HPGD P15428 1/20 0.43
HIF1A Q16665 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CRHR1 P34998 4/20 0.37
KDM4E B2RXH2 4/20 0.34
AR P10275 1/20 0.33
KMT2A Q03164 3/20 0.32
POLB P06746 1/20 0.32
RAD52 P43351 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
FDPS P14324 1/20 0.32
FPR3 P25089 2/20 0.31
TSPO P30536 2/20 0.31
TMEM97 Q5BJF2 2/20 0.31
HCAR1 Q9BXC0 3/20 0.31
MAPK1 P28482 2/20 0.31
CYP11B1 P15538 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28874167 0.81 ALDH1A1 (0.39) ALDH1A1CYP1A2CYP2D6HPGDHIF1A
Hydrochloric Acid SCHEMBL28874174 0.80 ALDH1A1 (0.38) ALDH1A1CYP1A2CYP2D6HPGDHIF1A
SCHEMBL13706025 0.71 CYP3A4 (0.43) ALDH1A1CYP1A2CYP2D6CRHR1KDM4E
SCHEMBL27164670 0.68 MAPK1 (0.56) KMT2APOLBMAPK1CYP11B1CYP11B2
SCHEMBL29657515 0.68 MAPK1 (0.56) KMT2APOLBMAPK1CYP11B1CYP11B2
SCHEMBL11052944 0.67 CRHR1 (0.38) ALDH1A1CRHR1KDM4EFPR3TSPO
SCHEMBL11052345 0.67 KDM4E (0.39) ALDH1A1HSD17B10CRHR1KDM4ESMN1; SMN2
SCHEMBL11056407 0.65 CRHR1 (0.34) ALDH1A1CRHR1KDM4EKMT2APOLB
SCHEMBL13589306 0.64 KDM4E (0.33) ALDH1A1CRHR1KDM4EKMT2ASMN1; SMN2
SCHEMBL5423379 0.64 L3MBTL1 (0.37) ALDH1A1HPGDCRHR1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462752-B Imidazole-phosphoramidite bidentate ligand, synthesis method thereof, metal catalyst prepared from imidazole-phosphoramidite bidentate ligand and application of metal catalyst 中国石油化工股份有限公司 2026-05-15 CN claimed
CN-119462752-A Imidazole-phosphoramidite bidentate ligand, synthesis method thereof, metal catalyst prepared from imidazole-phosphoramidite bidentate ligand and application of metal catalyst 中国石油化工股份有限公司 2025-02-18 CN claimed
CN-119462752-B Imidazole-phosphoramidite bidentate ligand, synthesis method thereof, metal catalyst prepared from imidazole-phosphoramidite bidentate ligand and application of metal catalyst 中国石油化工股份有限公司 2026-05-15 CN disclosed
CN-119462752-A Imidazole-phosphoramidite bidentate ligand, synthesis method thereof, metal catalyst prepared from imidazole-phosphoramidite bidentate ligand and application of metal catalyst 中国石油化工股份有限公司 2025-02-18 CN disclosed
WO-2022266768-A1 IRON-BASED COMPLEXES FOR USE IN THE CATALYSIS OF HYDROSILYLATION REACTIONS THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2022-12-29 WO disclosed
WO-2022187205-A1 UNSYMMETRICAL N-HETEROCYCLIC CARBENE CATALYSTS AND METHODS USING SAME RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2022-09-09 WO disclosed