Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27186195 | 1.00 | PIK3CA (0.34) | PIK3CASLC2A1CARM1CHRM4OPRL1 | |
| SCHEMBL12012377 | 0.71 | PIK3CA (0.50) | PIK3CACARM1CHRM4ALDH1A1MAPK1 | |
| SCHEMBL30853310 | 0.69 | LMNA (0.31) | HTT | |
| SCHEMBL27186160 | 0.69 | LMNA (0.31) | HTT | |
| SCHEMBL29168401 | 0.68 | NUDT1 (0.43) | PIK3CACHRM4OPRL1PDCD1CD274 | |
| SCHEMBL29844244 | 0.68 | PDK2 (0.32) | HTT | |
| SCHEMBL27186297 | 0.68 | PDK2 (0.32) | HTT | |
| SCHEMBL2488800 | 0.67 | CTSK (0.44) | PIK3CACHRM4PDCD1CD274 | |
| SCHEMBL2488799 | 0.67 | CTSK (0.44) | PIK3CACHRM4PDCD1CD274 | |
| SCHEMBL12012382 | 0.67 | CTSK (0.44) | PIK3CACHRM4PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |
| WO-2022187266-A1 | NOVEL SUBSTITUTED BICYCLI AZA-HETEROCYCLES AS SOS1 INHIBITORS | VIVA STAR BIOSCIENCES (SUZHOU) CO., LTD. (CN) | 2022-09-09 | — | — | WO | disclosed |