SCHEMBL2984458

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2993958	0.86	OPRM1 (0.41)	KDM4EL3MBTL1OPRM1ALOX5APFEN1
	SCHEMBL2986493	0.81	ALOX5AP (0.41)	KMT2AL3MBTL1OPRM1ALOX5APFEN1
	SCHEMBL2991863	0.79	KDM4E (0.47)	KMT2AMEN1KDM4ENPC1HSP90AA1
	SCHEMBL2996256	0.78	OPRM1 (0.34)	KMT2AMEN1KDM4EL3MBTL1OPRM1
	SCHEMBL2986635	0.78	PDE4B (0.34)	OPRM1ALOX5APFEN1MAP4K4GABRP
	SCHEMBL3692397	0.78	ALOX5AP (0.41)	KMT2AMEN1KDM4EL3MBTL1OPRM1
	SCHEMBL3692464	0.74	KEAP1 (0.43)	KDM4ENPC1RAB9ANPSR1L3MBTL1
	SCHEMBL3156151	0.72	KMT2A (0.59)	KMT2AMEN1KDM4ENPC1HSP90AA1
	SCHEMBL3689680	0.72	KDM4E (0.44)	KDM4EL3MBTL1OPRM1ALOX5APFEN1
	SCHEMBL3886973	0.70	ALDH1A1 (0.51)	KDM4EOPRM1MAP4K4PDE4BERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.