Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29849080 | 0.87 | MAPT (0.51) | MAPTL3MBTL1RAB9AALDH1A1POLB | |
| SCHEMBL22164501 | 0.82 | MAPT (0.47) | MAPTL3MBTL1RAB9AALDH1A1POLB | |
| SCHEMBL22164503 | 0.82 | MAPT (0.47) | MAPTL3MBTL1RAB9AALDH1A1POLB | |
| SCHEMBL22165582 | 0.79 | MAPT (0.46) | MAPTL3MBTL1RAB9AALDH1A1POLB | |
| SCHEMBL22165581 | 0.79 | MAPT (0.46) | MAPTL3MBTL1RAB9AALDH1A1POLB | |
| SCHEMBL8171111 | 0.78 | MAPT (0.43) | MAPTL3MBTL1RAB9AALDH1A1LMNA | |
| SCHEMBL27311606 | 0.74 | RAB9A (0.44) | MAPTRAB9APOLBTDP1MEN1 | |
| SCHEMBL19856430 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL18655432 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL17153016 | 0.72 | MAPT (0.41) | MAPTL3MBTL1RAB9AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008088690-A2 | A PROCESS FOR PREPARING DIAZABICYCLO[3.3.1] NONANE COMPOUNDS | MERCK & CO., INC. (US) | 2008-07-24 | — | — | WO | disclosed |