Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | METAP2 | P50579 | 1/20 | 0.54 |
| ▸ | METAP1 | P53582 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL28080599 | 0.88 | LMNA (0.68) | HSP90AA1LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL111242 | 0.86 | LMNA (0.65) | HSP90AA1LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL29851236 | 0.85 | KDR (0.71) | CYP1A2CYP3A4KDRHDAC6MEN1 | |
| SCHEMBL1695444 | 0.85 | KDR (0.71) | CYP1A2CYP3A4KDRHDAC6MEN1 | |
| SCHEMBL3549883 | 0.77 | CYP1A2 (0.71) | CYP1A2CYP3A4LMNAKDRHDAC6 | |
| SCHEMBL3415803 | 0.76 | LMNA (0.71) | HSP90AA1LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL28459061 | 0.74 | LMNA (0.69) | HSP90AA1LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL8458715 | 0.74 | ALDH1A1 (0.46) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28131091 | 0.74 | HSP90AA1 (0.68) | HSP90AA1LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL7360935 | 0.73 | HSP90AA1 (1.00) | HSP90AA1LMNAKDRMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945572-B | HBF pharmacological inducing compounds for the treatment of sickle cell anemia and beta-thalassemia | 周美吟 | 2025-01-28 | — | — | CN | disclosed |
| CN-111825611-B | 4(1H) -quinovone derivatives and uses thereof | 刘扶东 | 2022-09-09 | — | — | CN | disclosed |
| CN-114945572-A | HBF pharmacological inducing compounds for the treatment of sickle cell anemia and beta-thalassemia | 刘扶东 | 2022-08-26 | — | — | CN | disclosed |