Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29851236 | 0.85 | KDR (0.71) | KDRMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1695444 | 0.85 | KDR (0.71) | KDRMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12853981 | 0.76 | LMNA (0.68) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL30184687 | 0.76 | CCR1 (0.75) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL1282008 | 0.76 | CCR1 (0.75) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL27570425 | 0.75 | TSHR (0.68) | MEN1KMT2AMAPTSMN1; SMN2CASP3 | |
| SCHEMBL27508370 | 0.74 | CHRNB2 (0.45) | MAPTPOLBKDM4ENPC1RAB9A | |
| SCHEMBL3549883 | 0.74 | CYP1A2 (0.71) | KDRMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6260903 | 0.74 | KDR (1.00) | KDRMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL29434873 | 0.74 | KDR (1.00) | KDRMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4530931-A | 8-Quinoline carbanilates for the inhibition of lipolysis | USV PHARMACEUTICAL CORP. (US) | 1985-07-23 | — | — | US | claimed |
| US-4530931-A | 8-Quinoline carbanilates for the inhibition of lipolysis | USV PHARMACEUTICAL CORP. (US) | 1985-07-23 | — | — | US | disclosed |