Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1018949 | 1.00 | ASIC3 (0.55) | ASIC3KDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL502867 | 0.85 | KDM4E (0.62) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL29679578 | 0.85 | KDM4E (0.62) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL30679410 | 0.85 | MAOB (0.56) | ASIC3KDM4ELMNAALDH1A1MEN1 | |
| Imidazole SCHEMBL28793335 | 0.84 | HRH3 (0.45) | ASIC3KDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL9225779 | 0.84 | KDM4E (0.55) | ASIC3KDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL29720253 | 0.83 | KDM4E (0.54) | ASIC3KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL12436470 | 0.83 | KDM4E (0.54) | ASIC3KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL12444511 | 0.83 | KDM4E (0.54) | ASIC3KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL18745791 | 0.83 | PIK3CD (0.49) | ASIC3KDM4ELMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306730-A | Cyclic ether modified 3-cyano-4-arylaminoquinoline derivative as well as preparation method and application thereof | 河北医科大学 | 2025-01-14 | — | — | CN | disclosed |
| CN-118878470-A | Novel quetiapine analogue, and preparation method and application thereof | 北京安博睿达医药科技有限公司 | 2024-11-01 | — | — | CN | disclosed |
| EP-4402127-A1 | AMINOPYRIDINES AS ACTIVATORS OF PI3 KINASE | UCL Business Ltd (GB) | 2024-07-24 | — | — | EP | disclosed |
| CN-116283668-A | Diaryl ureas as CB1 allosteric modulators | 研究三角协会 | 2023-06-23 | — | — | CN | disclosed |
| WO-2023041905-A1 | AMINOPYRIDINES AS ACTIVATORS OF PI3 KINASE | UCL BUSINESS LTD (GB) | 2023-03-23 | — | — | WO | disclosed |
| WO-2022250525-A1 | SELF-ASSEMBLING LIGHT-ACTIVATED METALLODRUGS | UNIVERSITEIT LEIDEN (NL) | 2022-12-01 | — | — | WO | disclosed |
| CN-115397806-A | Aryl and heteroaryl compounds and their therapeutic use in conditions associated with altered activity of galactocerebrosidase | 增益治疗股份有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-113121562-B | Polycyclic compounds as inhibitors of bruton's tyrosine kinase | 詹森药业有限公司 | 2022-09-13 | — | — | CN | disclosed |
| US-11424006-B2 | Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide | PSOMAGEN, INC. (US) | 2022-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11424006-B2 | Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide | PNMT, MAOA, HNMT | ASIC3 2567/4885KDM4E 733/4885LMNA 2593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.