Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29927756 | 0.99 | ALDH1A1 (0.67) | ALDH1A1KDM4EL3MBTL1ATMSMN1; SMN2 | |
| SCHEMBL29852370 | 0.82 | LTA4H (0.52) | ALDH1A1KDM4EL3MBTL1ATMKMT2A | |
| SCHEMBL1946258 | 0.82 | L3MBTL1 (0.86) | ALDH1A1KDM4EL3MBTL1ATMSMN1; SMN2 | |
| SCHEMBL8250801 | 0.82 | ALDH1A1 (0.80) | ALDH1A1KDM4EL3MBTL1ATMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29927303 | 0.81 | LTA4H (0.51) | ALDH1A1KDM4EL3MBTL1ATMKMT2A | |
| Hydrochloric Acid SCHEMBL29927265 | 0.81 | LTA4H (0.51) | ALDH1A1KDM4EL3MBTL1ATMKMT2A | |
| SCHEMBL4850083 | 0.81 | ALDH1A1 (0.78) | ALDH1A1KDM4EL3MBTL1ATMSMN1; SMN2 | |
| Bromide SCHEMBL10462008 | 0.81 | L3MBTL1 (0.84) | ALDH1A1KDM4EL3MBTL1ATMSMN1; SMN2 | |
| SCHEMBL5178089 | 0.80 | ALDH1A1 (0.77) | ALDH1A1KDM4EL3MBTL1ATMSMN1; SMN2 | |
| SCHEMBL3701693 | 0.79 | ALDH1A1 (0.83) | ALDH1A1KDM4EL3MBTL1ATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929697-A | Azabenzimidazole compounds and medicaments | 日本新药株式会社 | 2022-08-19 | — | — | CN | disclosed |