Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.46 |
| ▸ | HSD11B2 | P80365 | 8/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 9/20 | 0.45 |
| ▸ | SSTR1 | P30872 | 5/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2984736 | 0.87 | HSD11B1 (0.48) | HSD11B1HSD11B2SSTR4SSTR1CNR1 | |
| SCHEMBL2989369 | 0.85 | HSD11B1 (0.46) | HSD11B1HSD11B2SSTR4SSTR1CNR1 | |
| SCHEMBL2990225 | 0.80 | SSTR4 (0.41) | HSD11B1HSD11B2SSTR4CNR1 | |
| SCHEMBL2987072 | 0.76 | SSTR4 (0.41) | HSD11B1HSD11B2SSTR4SSTR1 | |
| SCHEMBL2989160 | 0.76 | OPRM1 (0.43) | SSTR4SSTR1 | |
| SCHEMBL2987254 | 0.75 | SSTR4 (0.41) | HSD11B1HSD11B2SSTR4SSTR1 | |
| SCHEMBL2983411 | 0.73 | HSD11B1 (0.42) | HSD11B1HSD11B2SSTR4SSTR1CNR1 | |
| SCHEMBL2983764 | 0.73 | LMNA (0.58) | — | |
| SCHEMBL2979180 | 0.73 | CCR3 (0.56) | CNR1 | |
| SCHEMBL2985320 | 0.73 | SSTR4 (0.43) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786328-B2 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2010-08-31 | — | — | US | claimed |
| US-20070281954-A1 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-12-06 | — | — | US | claimed |
| US-7786328-B2 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2010-08-31 | — | — | US | disclosed |
| US-20070281954-A1 | Cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281954-A1 | Cyclohexyl-1,4-diamine compounds | DPYD, PKD1, AOC1 | HSD11B1 829/4885HSD11B2 652/4885SSTR4 1326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.