Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589772 | 0.87 | HPGD (0.44) | HPGDSLC6A4L3MBTL1MEN1LMNA | |
| SCHEMBL2078871 | 0.85 | L3MBTL1 (0.54) | HPGDSLC6A4L3MBTL1MEN1LMNA | |
| SCHEMBL28638978 | 0.83 | L3MBTL1 (0.52) | HPGDSLC6A4L3MBTL1LMNAKMT2A | |
| SCHEMBL17147389 | 0.83 | MAPT (0.46) | HPGDSLC6A4L3MBTL1MEN1LMNA | |
| SCHEMBL22558989 | 0.82 | L3MBTL1 (0.47) | HPGDL3MBTL1MEN1LMNAKMT2A | |
| SCHEMBL10594947 | 0.82 | TRPV1 (0.50) | HPGDL3MBTL1RAB9A | |
| SCHEMBL9643981 | 0.80 | ESR1 (0.41) | SLC6A4L3MBTL1MEN1LMNAKMT2A | |
| SCHEMBL29148791 | 0.80 | L3MBTL1 (0.50) | HPGDL3MBTL1MEN1LMNAKMT2A | |
| SCHEMBL441860 | 0.79 | KCNA3 (0.58) | HPGDL3MBTL1MEN1LMNAKMT2A | |
| SCHEMBL29860318 | 0.79 | KCNA3 (0.58) | HPGDL3MBTL1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12103902-B2 | Bicyclic compounds | VIVACE THERAPEUTICS, INC. (US) | 2024-10-01 | — | — | US | disclosed |
| US-20240025913-A1 | TERTIARY CARBOXAMIDE COMPOUNDS | VIVACE THERAPEUTICS, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20220298102-A1 | BICYCLIC COMPOUNDS | VIVACE THERAPEUTICS, INC. | 2022-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220298102-A1 | BICYCLIC COMPOUNDS | YAP1, TEAD2, TEAD3 | HPGD 1041/4885SLC6A4 4840/4885L3MBTL1 1959/4885 |
| US-20240025913-A1 | TERTIARY CARBOXAMIDE COMPOUNDS | YAP1, TFAM, PC | HPGD 1219/4885SLC6A4 4795/4885L3MBTL1 1921/4885 |
| US-12103902-B2 | Bicyclic compounds | YAP1, TEAD2, TEAD3 | HPGD 898/4885SLC6A4 4788/4885L3MBTL1 2253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.