Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29985287 | 0.80 | KDM4E (0.45) | DYRK1AADRA1ACSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL21056712 | 0.77 | NR4A2 (0.50) | ADRA1A | |
| SCHEMBL1658942 | 0.77 | ADRA1A (0.52) | DYRK1AADRA1ACSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29799903 | 0.75 | KDM4E (0.41) | DYRK1AADRA1ACSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11322639 | 0.75 | NOTUM (0.54) | DYRK1ACSNK2A2CSNK2BCSNK2A1F7 | |
| SCHEMBL15468562 | 0.73 | BAZ2B (0.54) | TSHRKDM4EALDH1A1CA12CA1 | |
| SCHEMBL25376076 | 0.72 | HPGD (0.60) | TSHRSMN1; SMN2KDM4EALDH1A1CA12 | |
| SCHEMBL19817369 | 0.72 | ADRA1A (0.40) | DYRK1AADRA1ACSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11157567 | 0.72 | — | — | |
| SCHEMBL68449 | 0.71 | ALDH1A1 (0.61) | TSHRCASP1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12466805-B2 | Pharmaceutical compounds | ALMAC DISCOVERY LIMITED (GB) | 2025-11-11 | — | — | US | disclosed |
| CN-109790146-B | Pharmaceutical compounds | 阿尔麦克探索有限公司 | 2022-08-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12466805-B2 | Pharmaceutical compounds | USP19, USP18, UBE2I | DYRK1A 4622/4885ADRA1A 3092/4885CSNK2A2 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.