Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29989920 | 0.92 | OPRD1 (0.48) | ALDH1A1MAPTLAP3MEN1LMNA | |
| SCHEMBL30051918 | 0.90 | ALDH1A1 (0.49) | ALDH1A1MAPTLAP3MEN1LMNA | |
| SCHEMBL29506415 | 0.90 | CTSB (0.42) | ALDH1A1MAPTLAP3MEN1LMNA | |
| SCHEMBL4093181 | 0.87 | MME (0.44) | OPRD1OPRM1OPRK1MME | |
| SCHEMBL31723030 | 0.87 | MME (0.44) | OPRD1OPRM1OPRK1MME | |
| SCHEMBL4093176 | 0.87 | MME (0.44) | OPRD1OPRM1OPRK1MME | |
| SCHEMBL29590916 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPTLAP3MEN1LMNA | |
| SCHEMBL30051649 | 0.86 | TERT (0.51) | ALDH1A1MAPTLAP3MEN1LMNA | |
| SCHEMBL7150981 | 0.85 | MAPT (0.53) | ALDH1A1MAPTLAP3MEN1LMNA | |
| SCHEMBL7553789 | 0.85 | MAPT (0.53) | ALDH1A1MAPTLAP3MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497604-B2 | RNase-PON1 fusion polypeptides and related compositions and methods | THERIPION, INC. (US) | 2025-12-16 | — | — | US | disclosed |
| US-20250154484-A1 | RNASE-PON1 FUSION POLYPEPTIDES AND RELATED COMPOSITIONS AND METHODS | THERIPION, INC. (US) | 2025-05-15 | — | — | US | disclosed |
| US-20250145977-A1 | METHODS FOR TREATING RHEUMATOID ARTHRITIS USING CTLA4-PON1 FUSION PROTEINS | THERIPION, INC. (US) | 2025-05-08 | — | — | US | disclosed |
| US-12258596-B2 | Polynucleotides encoding paraoxonase fusion polypeptides | THERIPION, INC. (US) | 2025-03-25 | — | — | US | disclosed |
| US-20250059525-A1 | POLYNUCLEOTIDES ENCODING PARAOXONASE FUSION POLYPEPTIDES | THERIPION, INC. (US) | 2025-02-20 | — | — | US | disclosed |
| US-12180521-B2 | Paraoxonase fusion polypeptides and related compositions and methods | THERIPION, INC. (US) | 2024-12-31 | — | — | US | disclosed |
| WO-2024259220-A1 | PON3 AND EVOLVED PON1 FUSION POLYPEPTIDES | THERIPION, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| CN-113366024-B | FGF21 mutant proteins and fusion proteins thereof | 上海翰森生物医药科技有限公司 | 2024-11-05 | — | — | CN | disclosed |
| US-20240294889-A1 | DNASE FUSION POLYPEPTIDES AND RELATED COMPOSITIONS AND METHODS | THERIPION, INC. (US) | 2024-09-05 | — | — | US | disclosed |
| US-20240101982-A1 | PARAOXONASE FUSION POLYPEPTIDES AND RELATED COMPOSITIONS AND METHODS | THERIPION, INC. | 2024-03-28 | — | — | US | disclosed |
| EP-4294916-A2 | DNASE FUSION POLYPEPTIDES AND RELATED COMPOSITIONS AND METHODS | Theripion, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| US-20230015291-A1 | DNASE FUSION POLYPEPTIDES AND RELATED COMPOSITIONS AND METHODS | THERIPION, INC. | 2023-01-19 | — | — | US | disclosed |
| WO-2022178090-A2 | DNASE FUSION POLYPEPTIDES AND RELATED COMPOSITIONS AND METHODS | THERIPION, INC. (US) | 2022-08-25 | — | — | WO | disclosed |