Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 7/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29867871 | 0.92 | ALDH1A1 (0.47) | OPRD1OPRM1OPRK1ALDH1A1MAPT | |
| SCHEMBL29506415 | 0.87 | CTSB (0.42) | OPRD1OPRM1OPRK1ALDH1A1MAPT | |
| SCHEMBL29630425 | 0.86 | OPRD1 (0.55) | OPRD1OPRM1OPRK1ALDH1A1MAPT | |
| SCHEMBL29531441 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTLAP3MEN1LMNA | |
| SCHEMBL14842720 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTLAP3MEN1LMNA | |
| SCHEMBL28724482 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTLAP3MEN1LMNA | |
| SCHEMBL31174338 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTLAP3MEN1LMNA | |
| SCHEMBL14842719 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTLAP3MEN1LMNA | |
| SCHEMBL30964329 | 0.83 | OPRD1 (0.44) | OPRD1OPRM1OPRK1ALDH1A1MAPT | |
| SCHEMBL7290758 | 0.82 | OPRD1 (0.46) | OPRD1OPRM1OPRK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220354957-A1 | PEPTIDES TARGETING MACROPHAGES, AND CONJUGATES, COMPOSITIONS, AND USES THEREOF | TWINPIG BIOLAB, INC. (KR) | 2022-11-10 | — | — | US | disclosed |