SCHEMBL29873398

SCHEMBL29873398

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nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 5/20 0.49
▸ NAALAD2 Q9Y3Q0 3/20 0.49
▸ RIMKLA Q8IXN7 1/20 0.49
▸ GRM8 O00222 1/20 0.44
▸ GRM6 O15303 1/20 0.44
▸ GRIN2D O15399 1/20 0.44
▸ GRIN3B O60391 1/20 0.44
▸ GSR P00390 1/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ GRIK1 P39086 1/20 0.44
▸ GRM5 P41594 1/20 0.44
▸ GRIA1 P42261 1/20 0.44
▸ GRIA2 P42262 1/20 0.44
▸ GRIA3 P42263 1/20 0.44
▸ SLC1A3 P43003 1/20 0.44
▸ SLC1A2 P43004 1/20 0.44
▸ SLC1A1 P43005 1/20 0.44
▸ GRIA4 P48058 1/20 0.44
▸ GRIN1 Q05586 1/20 0.44
▸ GRIN2A Q12879 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30099677 0.98 FOLH1 (0.47) FOLH1NAALAD2RIMKLAGRM8GRM6
SCHEMBL30099487 0.98 FOLH1 (0.47) FOLH1NAALAD2RIMKLAGRM8GRM6
SCHEMBL31480000 0.98 FOLH1 (0.47) FOLH1NAALAD2RIMKLAGRM8GRM6
SCHEMBL30040249 0.95 FOLH1 (0.51) FOLH1NAALAD2RIMKLAGRM8GRM6
SCHEMBL29539765 0.95 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGRM8GRM6
SCHEMBL30312227 0.94 DPP4 (0.50) FOLH1NAALAD2RIMKLAGRM8GRM6
SCHEMBL30040038 0.94 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGRM8GRM6
SCHEMBL30193271 0.94 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGRM8GRM6
SCHEMBL30193339 0.94 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGRM8GRM6
SCHEMBL31479997 0.92 DPP4 (0.49) FOLH1NAALAD2RIMKLAGRM8GRM6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250123280-A1 LABEL-FREE DETECTION OF PROTEASE ACTIVITY UNIV OREGON HEALTH & SCIENCE (US) 2025-04-17 — — US claimed
US-20220256889-A1 PEPTIDES THAT MODULATE CALCIUM-SENSING RECEPTOR ACTIVITY FOR MODULATING KOKUMI TASTE AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2022-08-18 — — US claimed
US-12569521-B2 Methods and compositions for treating inflammatory skin disease with recombinant microorganisms AZITRA INC (US) 2026-03-10 — — US disclosed
US-20250090599-A1 METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY SKIN DISEASE WITH RECOMBINANT MICROORGANISMS AZITRA INC. 2025-03-20 — — US disclosed
US-12208124-B2 Methods and compositions for treating inflammatory skin disease with recombinant microorganisms AZITRA INC. (US) 2025-01-28 — — US disclosed
CN-118853521-A Methods and compositions for treating inflammatory skin diseases with recombinant microorganisms 阿兹特拉公司 2024-10-29 — — CN disclosed
CN-111278447-B Methods and compositions for treating inflammatory skin diseases with recombinant microorganisms 阿兹特拉公司 2024-08-06 — — CN disclosed
WO-2023003984-A2 LABEL-FREE DETECTION OF PROTEASE ACTIVITY OREGON HEALTH & SCIENCE UNIVERSITY (US) 2023-01-26 — — WO disclosed
US-20220325072-A1 ZWITTERIONIC CROSSLINKERS, HYDROGELS COMPRISING ZWITTERIONIC CROSSLINKERS, AND METHODS FOR MAKING AND USING UNIVERSITY OF IDAHO 2022-10-13 — — US disclosed
US-20220256889-A1 PEPTIDES THAT MODULATE CALCIUM-SENSING RECEPTOR ACTIVITY FOR MODULATING KOKUMI TASTE AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2022-08-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12208124-B2 Methods and compositions for treating inflammatory skin disease with recombinant microorganisms CUTA, TLR9, CX3CR1 FOLH1 1806/4885NAALAD2 1291/4885RIMKLA 2104/4885
US-20220325072-A1 ZWITTERIONIC CROSSLINKERS, HYDROGELS COMPRISING ZWITTERIONIC CROSSLINKERS, AND METHODS FOR MAKING AND USING ASS1, GFER, ASIC1 FOLH1 3483/4885NAALAD2 498/4885RIMKLA 202/4885
US-12569521-B2 Methods and compositions for treating inflammatory skin disease with recombinant microorganisms CUTA, MAFG, LRBA FOLH1 667/4885NAALAD2 1596/4885RIMKLA 3178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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