Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FABP1 | P07148 | 1/20 | 0.40 |
| ▸ | FABP6 | P51161 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16041382 | 1.00 | KDM4E (0.44) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL1831586 | 0.86 | KDM4E (0.46) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL6439928 | 0.84 | TLR8 (0.47) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL21018364 | 0.84 | TLR8 (0.47) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL24568583 | 0.80 | HCAR3 (0.50) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL6442872 | 0.80 | HCAR3 (0.50) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL4969090 | 0.79 | FDPS (0.50) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL4969096 | 0.79 | FDPS (0.50) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL7465452 | 0.79 | FDPS (0.50) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL19581191 | 0.79 | KDM4E (0.46) | KDM4EHTTNPSR1L3MBTL1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114980976-A | Covalent RAS inhibitors and uses thereof | 锐新医药公司 | 2022-08-30 | — | — | CN | disclosed |