SCHEMBL2989003

SCHEMBL2989003

OCCc1ccc(O)c(O)c1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 3/20 0.43
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
ALOX5 P09917 1/20 0.43
BACE1 P56817 1/20 0.43
ESR2 Q92731 2/20 0.39
ESR1 P03372 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
NPY1R P25929 1/20 0.39
PTGS2 P35354 1/20 0.39
OPRD1 P41143 1/20 0.39
MTOR P42345 1/20 0.39
HK2 P52789 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
THPO P40225 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PRKCI P41743 1/20 0.38
TYR P14679 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30045892 1.00 KDM4E (0.43) KDM4EALDH1A1GAAMAPTALOX5
SCHEMBL2976454 0.86 TYR (0.44) KDM4EALDH1A1ESR2ESR1ADORA3
SCHEMBL272405 0.82 TYR (0.48) PRKCITYR
SCHEMBL2639710 0.81 KDM4E (0.40) KDM4EALDH1A1GAAMAPTALOX5
SCHEMBL28938776 0.79 ERCC1 (0.41) KDM4EALDH1A1GAAMAPTALOX5
SCHEMBL2510833 0.79 KDM4E (0.42) KDM4EALDH1A1GAAMAPTESR2
SCHEMBL5463172 0.78 TAAR1 (0.52) KDM4EALDH1A1MAPTMTORTHPO
SCHEMBL30046415 0.78 IAPP (0.57) KDM4EALDH1A1MAPTCYP3A4HSD17B10
SCHEMBL5445936 0.78 PRKCI (0.60) ALOX5PRKCITYR
SCHEMBL1951548 0.78 IAPP (0.57) KDM4EALDH1A1MAPTCYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents BIODERM RESEARCH (US) 2009-03-19 US claimed
CN-114245792-A Compound, polymer, composition for film formation, method for pattern formation, method for forming insulating film, method for producing compound, and method for producing iodine-containing vinyl polymer and acetylated derivative thereof 三菱瓦斯化学株式会社 2022-03-25 CN disclosed
WO-2021029395-A1 COMPOUND, POLYMER, COMPOSITION, COMPOSITION FOR FILM FORMATION, PATTERN FORMING METHOD, METHOD FOR FORMING INSULATING FILM, METHOD FOR PRODUCING COMPOUND, IODINE-CONTAINING VINYL POLYMER AND METHOD FOR PRODUCING ACETYLATED DERIVATIVE OF SAME 三菱瓦斯化学株式会社 2021-02-18 WO disclosed
US-20150030705-A1 TECHNIQUE AND METHOD FOR PRODUCING FUNCTIONAL MATERIAL ORIGINATED FROM ICE PLANT, AND FUNCTIONAL COMPONENT TSUJIKO CO., LTD (JP) 2015-01-29 US disclosed
EP-2813138-A1 TECHNIQUE AND METHOD FOR PRODUCING FUNCTIONAL MATERIAL ORIGINATED FROM ICE PLANT, AND FUNCTIONAL COMPONENT Tsujiko Co., Ltd. (JP) 2014-12-17 EP disclosed
EP-2143793-B1 GENES OF ENZYMES PARTICIPATING IN VITAMIN E BIOSYNTHESIS IN PARA RUBBER TREE BRIDGESTONE CORP (JP) 2013-09-25 EP disclosed
US-8372616-B2 Homogentisic acid geranylgeranyl transerase polypeptide BRIDGESTONE CORPORATION (JP) 2013-02-12 US disclosed
US-7777073-B2 Topical delivery system for antiaging and skin whitening agents BIODERM RESEARCH (US) 2010-08-17 US disclosed
US-20100186109-A1 GENES OF ENZYMES PARTICIPATING IN VITAMIN E BIOSYNTHESIS IN PARA RUBBER TREE BRIDGESTONE CORPORATION (JP) 2010-07-22 US disclosed
EP-2143793-A1 GENES OF ENZYMES PARTICIPATING IN VITAMIN E BIOSYNTHESIS IN PARA RUBBER TREE Bridgestone Corporation (JP) 2010-01-13 EP disclosed
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents BIODERM RESEARCH (US) 2009-03-19 US disclosed
EP-0378858-A2 Process for the preparation of branched thermoplastic polycarbonates GENERAL ELECTRIC COMPANY (US) 1990-07-25 EP disclosed
US-4022664-A HYDROLYSIS EISAI CO., LTD. (JA) 1977-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents TYR, MMP17, MMP1 KDM4E 1048/4885ALDH1A1 567/4885GAA 232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.