SCHEMBL2989042

SCHEMBL2989042

CCN(CC)c1ccc2cc(C(=O)c3ccc(C#N)cc3)c(=O)oc2c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.76
MEN1 O00255 10/20 0.65
KMT2A Q03164 10/20 0.65
MAPT P10636 7/20 0.65
ALDH1A1 P00352 6/20 0.65
KDM4E B2RXH2 6/20 0.65
HPGD P15428 4/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
ATM Q13315 3/20 0.65
USP2 O75604 2/20 0.65
HSD17B10 Q99714 2/20 0.65
CYP1A2 P05177 1/20 0.65
CYP2C19 P33261 1/20 0.65
SLC16A3 O15427 1/20 0.65
ALOX15 P16050 1/20 0.65
SLC16A1 P53985 1/20 0.65
CYP19A1 P11511 1/20 0.55
CTSS P25774 2/20 0.52
CTSK P43235 2/20 0.52
NPC1 O15118 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL304258 0.91 MAOB (0.86) MAOBMEN1KMT2AMAPTALDH1A1
SCHEMBL29363687 0.91 MAOB (0.86) MAOBMEN1KMT2AMAPTALDH1A1
SCHEMBL195935 0.87 MAOB (0.80) MAOBMEN1KMT2AMAPTALDH1A1
SCHEMBL2992592 0.87 MAOB (0.84) MAOBMEN1KMT2AMAPTALDH1A1
SCHEMBL6832440 0.86 MAOB (0.79) MAOBMEN1KMT2AMAPTALDH1A1
SCHEMBL5503728 0.86 MAPT (0.58) MAOBMEN1KMT2AMAPTALDH1A1
SCHEMBL30785604 0.86 MAOB (1.00) MAOBMEN1KMT2AMAPTALDH1A1
SCHEMBL52729 0.86 MAOB (1.00) MAOBMEN1KMT2AMAPTALDH1A1
SCHEMBL51872 0.86 MEN1 (0.82) MAOBMEN1KMT2AMAPTALDH1A1
SCHEMBL9321949 0.85 MAOB (0.98) MAOBMEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0022188-B1 CO-INITIATOR COMPOSITIONS FOR PHOTOPOLYMERIZATION CONTAINING 3-ACYL-SUBSTITUTED COUMARINS, PHOTOPOLYMERIZABLE COMPOSITION AND PHOTOGRAPHIC ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-03 EP claimed
US-4289844-A 3-KETO-COUMARIN DERIVATIVES, HIGH SPEED EASTMAN KODAK COMPANY (US) 1981-09-15 US claimed
US-4278751-A Photopolymerization co-initiator compositions comprising amine-substituted ketocoumarins and certain acetic acid derivative activators EASTMAN KODAK COMPANY (US) 1981-07-14 US claimed
EP-0022188-A2 Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-01-14 EP claimed
EP-3593786-B1 PHOTOCURABLE COMPOSITION AND DENTAL RESTORATION FILLING MATERIAL TOKUYAMA DENTAL CORP (JP) 2022-05-18 EP disclosed
US-11273104-B2 Photocurable composition and dental restoration filling material TOKUYAMA DENTAL CORPORATION (JP) 2022-03-15 US disclosed
EP-3427716-B1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2021-11-24 EP disclosed
CN-108697586-B Photopolymerization initiator and photocurable composition 株式会社德山齿科 2021-07-06 CN disclosed
US-20210095055-A1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION TOKUYAMA DENTAL CORPORATION (JP) 2021-04-01 US disclosed
US-20200069534-A1 PHOTOCURABLE COMPOSITION AND DENTAL RESTORATION FILLING MATERIAL TOKUYAMA DENTAL CORPORATION (JP) 2020-03-05 US disclosed
CN-110392563-A Photocurable composition and dental prosthetic material 株式会社德山齿科 2019-10-29 CN disclosed
EP-3427716-A1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION Tokuyama Dental Corporation (JP) 2019-01-16 EP disclosed
US-6133338-A TYPIFIED BY 6-METHACRYLOYLOXYHEXYL 2-THIOURACIL-5-CARBOXYLATE, A RADICAL-POLYMERIZABLE MONOMER, AND A POLYMERIZATION INITIATOR; DENTAL ADHESIVE; GOOD ADHESIVENESS TO NOBLE METALS AND ALLOYS THEREOF TOKUYAMA CORPORATION (JP) 2000-10-17 US disclosed
EP-0896043-A1 Adhesive TOKUYAMA CORPORATION (JP) 1999-02-10 EP disclosed
US-5744511-A BLEND OF COUMARIN DYES, ACID GENERATOR AND ARYL BORATE TOKUYAMA CORPORATION (JP) 1998-04-28 US disclosed
EP-0738928-A2 Visible-ray polymerization initiator and visible-ray polymerizable composition TOKUYAMA CORPORATION (JP) 1996-10-23 EP disclosed
US-4366228-A 3-KETOCOUMARIN DERIVATIVES AS PHOTOSENSITIZERS; ALPHA-PHENYLOXYALKYLENECARBOXYLIC ACIDS AS ACTIVATORS; HIGH SPEED EASTMAN KODAK COMPANY (US) 1982-12-28 US disclosed
US-4289844-A 3-KETO-COUMARIN DERIVATIVES, HIGH SPEED EASTMAN KODAK COMPANY (US) 1981-09-15 US disclosed
US-4278751-A Photopolymerization co-initiator compositions comprising amine-substituted ketocoumarins and certain acetic acid derivative activators EASTMAN KODAK COMPANY (US) 1981-07-14 US disclosed
EP-0022188-A2 Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11273104-B2 Photocurable composition and dental restoration filling material H1-0, REV1, RER1 MAOB 938/4885MEN1 1122/4885KMT2A 3632/4885
US-20210095055-A1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION INO80C, JAK2, PCNA MAOB 944/4885MEN1 2856/4885KMT2A 444/4885
US-20200069534-A1 PHOTOCURABLE COMPOSITION AND DENTAL RESTORATION FILLING MATERIAL REV1, H1-0, RAD51 MAOB 959/4885MEN1 1293/4885KMT2A 3697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.