Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28891924 | 0.82 | ITGB3 (0.49) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL30014770 | 0.81 | HRH3 (0.38) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL31522165 | 0.79 | CXCR4 (0.37) | HRH3 | |
| SCHEMBL28891983 | 0.79 | GNAO1 (0.44) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL28868776 | 0.76 | ITGB3 (0.35) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL28868783 | 0.76 | ITGB3 (0.35) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL6043619 | 0.74 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL28891925 | 0.74 | GNAO1 (0.48) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL6044711 | 0.73 | NPC1 (0.31) | — | |
| SCHEMBL28957069 | 0.73 | GNAO1 (0.50) | TPSAB1TPSD1TPSG1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232108-B | SOS1 degradation agent and preparation method and application thereof | 领泰生物医药(绍兴)有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-115232114-B | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-115232114-A | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232111-A | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232108-A | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |