Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.32 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.32 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28868783 | 1.00 | ITGB3 (0.35) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL28891983 | 0.85 | GNAO1 (0.44) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL27119127 | 0.83 | TDP1 (0.38) | ITGB3ITGA2BGNAO1SLC6A2SLC6A4 | |
| SCHEMBL28891924 | 0.82 | ITGB3 (0.49) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL30015135 | 0.81 | ITGB3 (0.32) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL31522161 | 0.80 | KDM4E (0.38) | GNAO1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL30013612 | 0.79 | ITGB3 (0.48) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL27153790 | 0.79 | ITGB3 (0.48) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL29892104 | 0.76 | TPSAB1 (0.38) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL28696587 | 0.75 | SIGMAR1 (0.36) | DRD2HTR2AHTR2CHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232108-B | SOS1 degradation agent and preparation method and application thereof | 领泰生物医药(绍兴)有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-115232114-B | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-115232114-A | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232111-A | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232108-A | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |