Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 18/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893138 | 0.88 | NAMPT (0.53) | NAMPTMAPT | |
| SCHEMBL29893191 | 0.87 | NAMPT (0.50) | NAMPTMAPT | |
| SCHEMBL27077360 | 0.85 | TACR3 (0.55) | NAMPTMAPTROCK2ROCK1 | |
| SCHEMBL27077366 | 0.83 | NAMPT (0.51) | NAMPTMAPT | |
| SCHEMBL29893608 | 0.82 | TDO2 (0.49) | NAMPT | |
| SCHEMBL27077334 | 0.81 | TDO2 (0.44) | NAMPTMAPT | |
| SCHEMBL29894100 | 0.81 | ADORA3 (0.46) | NAMPTMAPT | |
| SCHEMBL29892985 | 0.81 | KDM4E (0.49) | MAPT | |
| SCHEMBL29893836 | 0.81 | SCN9A (0.54) | NAMPT | |
| SCHEMBL27077346 | 0.80 | ADRA1D (0.44) | NAMPTMAPTROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |