Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29894100 | 0.91 | ADORA3 (0.46) | KDM4ESMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL29893059 | 0.88 | NAMPT (0.51) | PPARD | |
| SCHEMBL29893119 | 0.86 | P2RY14 (0.43) | SLC6A2P2RY14ADORA3MAPK1MAP2K4 | |
| SCHEMBL29893288 | 0.86 | MLYCD (0.44) | KDM4ESMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL29893608 | 0.86 | TDO2 (0.49) | KDM4ESMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL29893305 | 0.85 | P2RY14 (0.48) | KDM4EALDH1A1HPGDMAPTDHODH | |
| SCHEMBL27077390 | 0.85 | KDM4E (0.43) | KDM4ETDP1MEN1KMT2APPARD | |
| SCHEMBL29893160 | 0.85 | TDO2 (0.42) | KDM4ESMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL25981084 | 0.85 | SMN1; SMN2 (0.67) | KDM4ESMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL29893404 | 0.84 | MAPK1 (0.44) | KDM4EESR1ESR2DHODHACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |