Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893417 | 0.90 | LMNA (0.47) | TDO2MRGPRX4IDO1CSNK2A1KDR | |
| SCHEMBL29892985 | 0.85 | KDM4E (0.49) | TDO2PDGFRBPDGFRAIDO1KDM4E | |
| SCHEMBL27077390 | 0.83 | KDM4E (0.43) | MRGPRX4CSNK2A1KDM4EMEN1KMT2A | |
| SCHEMBL27077542 | 0.81 | HDAC4 (0.41) | TDO2KDRALDH1A1LMNARAB9A | |
| SCHEMBL29893108 | 0.81 | HDAC4 (0.44) | TDO2KDR | |
| SCHEMBL29893225 | 0.80 | CSNK2A1 (0.42) | MRGPRX4CSNK2A1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27077496 | 0.79 | KDM4E (0.46) | CSNK2A1CSNK2A2CSNK2BKDM4EALDH1A1 | |
| SCHEMBL29893923 | 0.79 | KDM4E (0.46) | CSNK2A1CSNK2A2CSNK2BKDM4EALDH1A1 | |
| SCHEMBL29894100 | 0.76 | ADORA3 (0.46) | TDO2IDO1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29893059 | 0.76 | NAMPT (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |