Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27077393 | 1.00 | ADH5 (0.43) | ADH5ALDH1A1SCN9ACYP19A1CYP11B1 | |
| SCHEMBL29893719 | 0.85 | PSEN1 (0.50) | TLR2TLR1 | |
| SCHEMBL27077585 | 0.83 | KDM4E (0.38) | ERAP1ERAP2KDM4ETLR2TLR1 | |
| SCHEMBL29893030 | 0.83 | KDM4E (0.38) | ERAP1ERAP2KDM4ETLR2TLR1 | |
| SCHEMBL27077390 | 0.82 | KDM4E (0.43) | ERAP1ERAP2KDM4ECSNK2A1CETP | |
| SCHEMBL29893923 | 0.79 | KDM4E (0.46) | ALDH1A1KDM4ECSNK2A1 | |
| SCHEMBL27077496 | 0.79 | KDM4E (0.46) | ALDH1A1KDM4ECSNK2A1 | |
| SCHEMBL27077449 | 0.78 | TLR2 (0.54) | TLR2TLR1 | |
| SCHEMBL29892985 | 0.77 | KDM4E (0.49) | ALDH1A1KDM4E | |
| SCHEMBL29893160 | 0.74 | TDO2 (0.42) | ALDH1A1KDM4ECSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |