Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.50 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255377 | 1.00 | P2RX1 (0.50) | P2RX1MPIARGRIN2BTRPV1 | |
| SCHEMBL27647157 | 0.91 | P2RX1 (0.48) | P2RX1MPIARGRIN2BTRPV1 | |
| SCHEMBL3147185 | 0.84 | GPR3 (0.50) | MPIGPR3 | |
| SCHEMBL24384600 | 0.83 | AR (0.43) | P2RX1ARKCNH2WDR5RHEB | |
| SCHEMBL7934039 | 0.83 | AR (0.43) | P2RX1ARKCNH2WDR5RHEB | |
| SCHEMBL22407023 | 0.79 | AR (0.46) | P2RX1ARCNR1GPR3MGLL | |
| SCHEMBL2655862 | 0.79 | GRIN2B (0.51) | GRIN2BTRPV1CCR6KCNH2 | |
| SCHEMBL2318592 | 0.78 | WDR5 (0.42) | KCNH2WDR5 | |
| SCHEMBL31421812 | 0.77 | RXRA (0.44) | P2RX1RXRA | |
| SCHEMBL23519084 | 0.77 | RXRA (0.44) | P2RX1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110799490-B | 3-arylpropionamide compound and method for producing 3-arylpropionate compound | 住友化学株式会社 | 2023-05-02 | — | — | CN | disclosed |
| CN-112159329-B | Co-production preparation method of o-amino trifluoromethoxybenzene and m-amino trifluoromethoxybenzene | 大连奇凯医药科技有限公司 | 2022-09-06 | — | — | CN | disclosed |