Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | OGG1 | O15527 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28227071 | 0.91 | WDR5 (0.40) | WDR5KCNH2KMT2AOGG1POLB | |
| SCHEMBL260934 | 0.84 | KIF11 (0.47) | KMT2ALMNASMN1; SMN2KIF11MEN1 | |
| SCHEMBL8371469 | 0.83 | PGR (0.44) | WDR5KCNH2KMT2AOGG1POLB | |
| SCHEMBL13019816 | 0.79 | ALDH1A1 (0.46) | KMT2ALMNASMN1; SMN2KIF11MEN1 | |
| SCHEMBL29893341 | 0.78 | P2RX1 (0.50) | WDR5KCNH2 | |
| SCHEMBL255377 | 0.78 | P2RX1 (0.50) | WDR5KCNH2 | |
| SCHEMBL8888581 | 0.77 | KMT2A (0.42) | WDR5KCNH2KMT2AOGG1POLB | |
| SCHEMBL9588829 | 0.77 | HSD11B1 (0.49) | KMT2AOGG1POLBHTR2AMEN1 | |
| SCHEMBL17859584 | 0.77 | HSD11B1 (0.46) | KMT2AOGG1POLBHTR2AMEN1 | |
| SCHEMBL3374117 | 0.77 | PPARA (0.64) | KMT2AOGG1MEN1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108285409-B | Method for synthesizing tert-butoxy substituted styrene and derivatives thereof | 徐州博康信息化学品有限公司 | 2022-03-15 | — | — | CN | claimed |
| EP-0307106-B1 | P- OR M-TERT BUTOXYPHENETHYL ALCOHOL AND PROCESS FOR PREPARING THE SAME | HOKKO CHEMICAL INDUSTRY CO., LTD (JP) | 1992-01-15 | — | — | EP | claimed |
| EP-0307106-A1 | P- or m-tert butoxyphenethyl alcohol and process for preparing the same | HOKKO CHEMICAL INDUSTRY CO., LTD (JP) | 1989-03-15 | — | — | EP | claimed |
| CN-108285409-B | Method for synthesizing tert-butoxy substituted styrene and derivatives thereof | 徐州博康信息化学品有限公司 | 2022-03-15 | — | — | CN | disclosed |
| US-20210338610-A1 | AMINO-ARYL-BENZAMIDE COMPOUNDS AND METHODS OF USE THEREOF | HEPANOVA, INC. | 2021-11-04 | — | — | US | disclosed |
| US-11000491-B2 | Amino-aryl-benzamide compounds and methods of use thereof | HEPANOVA, INC. (US) | 2021-05-11 | — | — | US | disclosed |
| US-10035790-B2 | RORγ modulators | EXELIXIS, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-10035790-B2 | RORγ modulators | EXELIXIS, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| CN-108285409-A | A method of the Styrene and its derivatives of synthesis tert-butoxy substitution | 上海博栋化学科技有限公司 | 2018-07-17 | — | — | CN | disclosed |
| US-20180072677-A1 | Peptidomimetics and Methods of Using the Same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2018-03-15 | — | — | US | disclosed |
| US-20180072677-A1 | Peptidomimetics and Methods of Using the Same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2018-03-15 | — | — | US | disclosed |
| US-20060224011-A1 | Catalyst composition and process for producing cross-coupled compound using same | TOSOH CORPORATION | 2006-10-05 | — | — | US | disclosed |
| EP-1707263-A1 | Catalyst composition comprising an alkylene diamine-nickel complex and process for producing a cross-coupled compound using the same | Tosoh Corporation (JP) | 2006-10-04 | — | — | EP | disclosed |
| EP-0790251-B1 | Preparation and use of (3-alkoxyphenyl) magnesium chlorides | GRUENENTHAL GMBH (DE) | 2002-12-04 | — | — | EP | disclosed |
| CN-1075075-C | Preparation and use of (3-alkoxyphenyl) magnesium chlorides | GRUENETHAL GMBH (DE) | 2001-11-21 | — | — | CN | disclosed |
| US-5852216-A | Preparation and use of (3-alkoxy-phenyl) magnesium chlorides | GRUENENTHAL GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| CN-1166491-A | Preparation and use of (3-alkoxyphenyl) magnesium chlorides | GRUENENTHAL GMBH (DE) | 1997-12-03 | — | — | CN | disclosed |
| EP-0790251-A2 | Preparation and use of (3-alkoxyphenyl) magnesium chlorides | Grünenthal GmbH (DE) | 1997-08-20 | — | — | EP | disclosed |
| EP-0307106-B1 | P- OR M-TERT BUTOXYPHENETHYL ALCOHOL AND PROCESS FOR PREPARING THE SAME | HOKKO CHEMICAL INDUSTRY CO., LTD (JP) | 1992-01-15 | — | — | EP | disclosed |
| EP-0307106-A1 | P- or m-tert butoxyphenethyl alcohol and process for preparing the same | HOKKO CHEMICAL INDUSTRY CO., LTD (JP) | 1989-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10035790-B2 | RORγ modulators | RORB, RORA, RORC | WDR5 2343/4885KCNH2 1711/4885KMT2A 2258/4885 |
| US-20060224011-A1 | Catalyst composition and process for producing cross-coupled compound using same | C5, TST, PYM1 | WDR5 1060/4885KCNH2 234/4885KMT2A 1683/4885 |
| US-11000491-B2 | Amino-aryl-benzamide compounds and methods of use thereof | AADAC, GOT2, ABAT | WDR5 1977/4885KCNH2 4525/4885KMT2A 771/4885 |
| US-20180072677-A1 | Peptidomimetics and Methods of Using the Same | OPRM1, OPRL1, OPRD1 | WDR5 3748/4885KCNH2 2129/4885KMT2A 3829/4885 |
| US-20210338610-A1 | AMINO-ARYL-BENZAMIDE COMPOUNDS AND METHODS OF USE THEREOF | AADAC, GOT2, ABAT | WDR5 1977/4885KCNH2 4525/4885KMT2A 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.