Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28846456 | 1.00 | MAPK1 (0.46) | MAPK1SMN1; SMN2HTTGRM5HPGD | |
| SCHEMBL24941149 | 0.76 | ADORA2A (0.41) | KMT2ATDP1KDM4E | |
| SCHEMBL29910078 | 0.74 | HTR1A (0.40) | HTTGRM5ALDH1A1KMT2AKDM4E | |
| SCHEMBL24941131 | 0.74 | HTR1A (0.40) | HTTGRM5ALDH1A1KMT2AKDM4E | |
| SCHEMBL29893703 | 0.73 | AOC1 (0.42) | KMT2AKDM4EMAPT | |
| SCHEMBL21555613 | 0.67 | TYR (0.46) | SMN1; SMN2HTTGRM5ALDH1A1KMT2A | |
| SCHEMBL26653890 | 0.65 | MEN1 (0.41) | KMT2ATDP1KDM4EMAPT | |
| SCHEMBL24719019 | 0.64 | ALDH1A1 (0.54) | HTTALDH1A1KMT2AKDM4EPKM | |
| SCHEMBL30146401 | 0.64 | ALDH1A1 (0.54) | HTTALDH1A1KMT2AKDM4EPKM | |
| SCHEMBL28437659 | 0.63 | HPGD (0.56) | MAPK1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055026-A1 | COMPOUNDS AS CD73 INHIBITORS | Bioardis LLC (US) | 2022-09-14 | — | — | EP | disclosed |
| CN-114945578-A | Compounds as CD73 inhibitors | 博奥阿迪斯生物科技公司 | 2022-08-26 | — | — | CN | disclosed |