Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2998988 | 1.00 | LMNA (0.41) | LMNAMEN1KMT2ANR1I2CHRM2 | |
| SCHEMBL2994298 | 1.00 | LMNA (0.41) | LMNAMEN1KMT2ANR1I2CHRM2 | |
| SCHEMBL2988743 | 1.00 | LMNA (0.41) | LMNAMEN1KMT2ANR1I2CHRM2 | |
| SCHEMBL2990116 | 1.00 | LMNA (0.41) | LMNAMEN1KMT2ANR1I2CHRM2 | |
| SCHEMBL2992903 | 0.99 | LMNA (0.39) | LMNAMEN1KMT2ANR1I2CHRM2 | |
| SCHEMBL2994158 | 0.95 | ALDH1A1 (0.42) | LMNAKMT2ACYP3A4MAPTHTR2B | |
| SCHEMBL2991805 | 0.91 | IKBKB (0.40) | LMNAKMT2ACYP3A4MAPTHTR2B | |
| SCHEMBL1734068 | 0.90 | ALDH1A1 (0.36) | LMNAKMT2AMAPTHTR2BPRKCA | |
| SCHEMBL1735523 | 0.90 | ALDH1A1 (0.36) | LMNAKMT2AMAPTHTR2BPRKCA | |
| SCHEMBL1734018 | 0.90 | ALDH1A1 (0.36) | LMNAKMT2AMAPTHTR2BPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778975-B2 | Helicobacter pylori eradicating agent having inhibitory activity on gastric acid secretion | Link Geonomics, Inc. (JP) | 2014-07-15 | — | — | US | disclosed |
| EP-2103608-B1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | ARIGEN PHARMACEUTICALS INC (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-20100173944-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | ARIGEN PHARMACEUTICALS, INC. (JP) | 2010-07-08 | — | — | US | disclosed |
| EP-2103608-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | Arigen, Pharmaceuticals, Inc. (JP) | 2009-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173944-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | GIPR, PGC, SLC10A2 | LMNA 4875/4885MEN1 3075/4885KMT2A 4468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.