Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994158 | 0.93 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2CA9MAPTHPGD | |
| SCHEMBL2992903 | 0.92 | LMNA (0.39) | ALDH1A1MAPTCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL2994298 | 0.91 | LMNA (0.41) | ALDH1A1SMN1; SMN2MAPTCYP3A4LMNA | |
| SCHEMBL2989663 | 0.91 | LMNA (0.41) | ALDH1A1SMN1; SMN2MAPTCYP3A4LMNA | |
| SCHEMBL2988743 | 0.91 | LMNA (0.41) | ALDH1A1SMN1; SMN2MAPTCYP3A4LMNA | |
| SCHEMBL2990116 | 0.91 | LMNA (0.41) | ALDH1A1SMN1; SMN2MAPTCYP3A4LMNA | |
| SCHEMBL2998988 | 0.91 | LMNA (0.41) | ALDH1A1SMN1; SMN2MAPTCYP3A4LMNA | |
| SCHEMBL8503271 | 0.90 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MAPTHPGDKDM4E | |
| SCHEMBL31515431 | 0.89 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPTHPGDKDM4E | |
| SCHEMBL2986583 | 0.88 | ALDH1A1 (0.38) | IKBKBALDH1A1SMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778975-B2 | Helicobacter pylori eradicating agent having inhibitory activity on gastric acid secretion | Link Geonomics, Inc. (JP) | 2014-07-15 | — | — | US | disclosed |
| CN-101553480-B | Helicobacter pylori degerming agent with gastric acid secretion inhibiting effect | ARIGEN PHARMACEUTICALS INC | 2013-06-05 | — | — | CN | disclosed |
| EP-2103608-B1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | ARIGEN PHARMACEUTICALS INC (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-20100173944-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | ARIGEN PHARMACEUTICALS, INC. (JP) | 2010-07-08 | — | — | US | disclosed |
| CN-101553480-A | Helicobacter pylori degerming agent with gastric acid secretion inhibiting effect | ARIGEN PHARMACEUTICALS INC (JP) | 2009-10-07 | — | — | CN | disclosed |
| EP-2103608-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | Arigen, Pharmaceuticals, Inc. (JP) | 2009-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173944-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | GIPR, PGC, SLC10A2 | IKBKB 537/4885ALDH1A1 1629/4885SMN1; SMN2 4682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.