Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456130 | 0.84 | AKR1B1 (0.52) | ALOX15CES2GALR3CYP1A2CYP2C9 | |
| SCHEMBL21582058 | 0.84 | ALOX15 (0.45) | DGAT1ALOX15CES2GALR3CYP1A2 | |
| SCHEMBL29738013 | 0.84 | AKR1B1 (0.52) | ALOX15CES2GALR3CYP1A2CYP2C9 | |
| SCHEMBL538344 | 0.83 | DGAT1 (0.55) | DGAT1CYP1A2CYP2C9KMT2AMEN1 | |
| SCHEMBL31551664 | 0.83 | DGAT1 (0.55) | DGAT1CYP1A2CYP2C9KMT2AMEN1 | |
| SCHEMBL15658116 | 0.81 | MAPT (0.46) | ALOX15CES2GALR3CYP1A2CYP2C9 | |
| SCHEMBL28875498 | 0.80 | MEN1 (0.58) | KMT2AMEN1CA2 | |
| SCHEMBL3474780 | 0.79 | SIRT1 (0.42) | DGAT1KMT2AMEN1SIRT1NPSR1 | |
| SCHEMBL12473692 | 0.79 | DGAT1 (0.50) | DGAT1KMT2AMEN1PTGDR2SIRT1 | |
| SCHEMBL2951923 | 0.79 | PYCR1 (0.41) | DGAT1SIRT1GAASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115003671-B | JNK inhibitors, pharmaceutical compositions and uses thereof | 武汉朗来科技发展有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-115003671-A | JNK inhibitors, pharmaceutical compositions and uses thereof | 武汉朗来科技发展有限公司 | 2022-09-02 | — | — | CN | disclosed |