Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | OGG1 | O15527 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30354629 | 0.83 | RXRA (0.51) | PYCR1MEN1KMT2ALMNAMAPT | |
| SCHEMBL1922484 | 0.83 | MAPT (0.43) | PYCR1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL5985 | 0.83 | RXRA (0.51) | PYCR1MEN1KMT2ALMNAMAPT | |
| SCHEMBL3472224 | 0.82 | MTNR1A (0.40) | SMN1; SMN2PYCR1MEN1KMT2AMAPT | |
| SCHEMBL2702114 | 0.81 | ICMT (0.45) | MEN1KMT2AHTT | |
| SCHEMBL23997364 | 0.81 | OGG1 (0.46) | SMN1; SMN2PYCR1MEN1KMT2ALMNA | |
| SCHEMBL29897640 | 0.79 | DGAT1 (0.43) | SIRT1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL15661539 | 0.79 | PDE10A (0.45) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL9539850 | 0.79 | MEN1 (0.44) | SMN1; SMN2PYCR1MEN1KMT2ALMNA | |
| SCHEMBL13751380 | 0.79 | HPGD (0.45) | SMN1; SMN2PYCR1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134708-A1 | THIAZOLOPYRIDYL AMIDE DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | BEIGENE , LTD. (KY) | 2023-07-20 | — | — | WO | disclosed |
| WO-2010149359-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF BENZIMIDAZOLECARBOXYLIC ACIDS | LONZA LTD (CH) | 2010-12-29 | — | — | WO | disclosed |