Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL8434602 | 1.00 | ALDH1A1 (0.64) | ALDH1A1TSHRALOX15AKR1C3KDM4E | |
| Phthalic Acid SCHEMBL8749968 | 0.96 | ALDH1A1 (0.58) | ALDH1A1TSHRALOX15AKR1C3KDM4E | |
| Styrene SCHEMBL2118111 | 0.88 | ALDH1A1 (0.54) | ALDH1A1TSHRALOX15AKR1C3KDM4E | |
| Salicylic Acid SCHEMBL5943117 | 0.88 | ALDH1A1 (0.69) | ALDH1A1TSHRALOX15KDM4ECA12 | |
| Styrene SCHEMBL27834603 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TSHRALOX15AKR1C3KDM4E | |
| Phthalic Acid SCHEMBL27931679 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TSHRALOX15AKR1C3KDM4E | |
| Styrene SCHEMBL1955286 | 0.85 | ALDH1A1 (0.78) | ALDH1A1TSHRAKR1C3SMN1; SMN2MAPT | |
| Styrene SCHEMBL272448 | 0.85 | ALDH1A1 (0.78) | ALDH1A1TSHRAKR1C3SMN1; SMN2MAPT | |
| Styrene SCHEMBL28935148 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15AKR1C3KDM4E | |
| Styrene SCHEMBL9011439 | 0.83 | ALDH1A1 (0.74) | ALDH1A1TSHRAKR1C3SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120134943-A1 | Topical Compositions Comprising An Alkoxylated Diphenylacrylate Compound And An Aryl Carboxylic Ester | ELC MANAGEMENT LLC | 2012-05-31 | — | — | US | claimed |
| EP-2427181-A2 | TOPICAL COMPOSITIONS COMPRISING AN ALKOXYLATED DIPHENYLACRYLATE COMPOUND AND AN ARYL CARBOXYLIC ESTER | ELC Management LLC (US) | 2012-03-14 | — | — | EP | claimed |
| WO-2010129321-A2 | TOPICAL COMPOSITIONS COMPRISING AN ALKOXYLATED DIPHENYLACRYLATE COMPOUND AND AN ARYL CARBOXYLIC ESTER | ELC MANAGEMENT LLC (US) | 2010-11-11 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120134943-A1 | Topical Compositions Comprising An Alkoxylated Diphenylacrylate Compound And An Aryl Carboxylic Ester | CUTA, TYR, ACMSD | ALDH1A1 42/4885TSHR 4825/4885ALOX15 708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.