Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131823 | 0.82 | ATM (0.47) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL29902882 | 0.82 | TSHR (0.47) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL2729354 | 0.81 | TDP1 (0.53) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL5674809 | 0.81 | TDP1 (0.53) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL8729537 | 0.81 | POLB (0.49) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL13523692 | 0.81 | KMT2A (0.53) | LMNAMEN1KMT2AALDH1A1RECQL | |
| Methane SCHEMBL28528368 | 0.80 | TDP1 (0.51) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL28847424 | 0.80 | ATM (0.51) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL29902863 | 0.80 | LMNA (0.42) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL29902892 | 0.80 | ATM (0.51) | LMNAMEN1KMT2AALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077316-A1 | BENZIMIDAZOLE DERIVATIVES | Pfizer Inc. (US) | 2022-10-26 | — | — | EP | disclosed |