Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | GFER | P55789 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | TRIM33 | Q9UPN9 | 3/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | SALL4 | Q9UJQ4 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20889674 | 0.85 | GAA (0.74) | ALDH1A1GAAKDM4EGFERMAPT | |
| SCHEMBL5165984 | 0.84 | ALDH1A1 (0.96) | ALDH1A1GAAKDM4EGFERMAPT | |
| SCHEMBL7975156 | 0.81 | ADORA1 (0.81) | ALDH1A1GAAKDM4EGFERMAPT | |
| SCHEMBL7977482 | 0.81 | ADORA1 (0.76) | ALDH1A1GAAKDM4EGFERMAPT | |
| SCHEMBL6643063 | 0.81 | ALDH1A1 (0.67) | ALDH1A1GAAKDM4EGFERMAPT | |
| SCHEMBL1966039 | 0.81 | ALDH1A1 (0.67) | ALDH1A1GAAKDM4EGFERMAPT | |
| SCHEMBL2986663 | 0.80 | ADORA1 (0.79) | ALDH1A1GAAKDM4EGFERMAPT | |
| SCHEMBL1967802 | 0.79 | ALDH1A1 (0.65) | ALDH1A1GAAKDM4EGFERMAPT | |
| SCHEMBL1970733 | 0.79 | ALDH1A1 (0.65) | ALDH1A1GAAKDM4EGFERMAPT | |
| SCHEMBL13464359 | 0.77 | SALL4 (0.64) | ALDH1A1GAAKDM4EGFERMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100173930-A1 | Certain Chemical Entities, Compositions and Methods | CYTOKINETICS, INC. | 2010-07-08 | — | — | US | claimed |
| WO-2008016648-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-02-07 | — | — | WO | claimed |
| US-20100173930-A1 | Certain Chemical Entities, Compositions and Methods | CYTOKINETICS, INC. | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173930-A1 | Certain Chemical Entities, Compositions and Methods | TNNC1, TNNI3, TNNT2 | ALDH1A1 3165/4885GAA 820/4885KDM4E 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.